Dissociation of choice formation and choice-correlated activity in macaque visual cortex

Robbe L.T. Goris, Corey M. Ziemba, Gabriel M. Stine, Eero Simoncelli, J. Anthony Movshon

Research output: Contribution to journalArticle

Abstract

Responses of individual task-relevant sensory neurons can predict monkeys’ trial-by-trial choices in perceptual decision-making tasks. Choice-correlated activity has been interpreted as evidence that the responses of these neurons are causally linked to perceptual judgments. To further test this hypothesis, we studied responses of orientation-selective neurons in V1 and V2 while two macaque monkeys performed a fine orientation discrimination task. Although both animals exhibited a high level of neuronal and behavioral sensitivity, only one exhibited choice-correlated activity. Surprisingly, this correlation was negative: when a neuron fired more vigorously, the animal was less likely to choose the orientation preferred by that neuron. Moreover, choice-correlated activity emerged late in the trial, earlier in V2 than in V1, and was correlated with anticipatory signals. Together, these results suggest that choice-correlated activity in task-relevant sensory neurons can reflect postdecision modulatory signals.

Original languageEnglish (US)
Pages (from-to)5195-5203
Number of pages9
JournalJournal of Neuroscience
Volume37
Issue number20
DOIs
StatePublished - May 17 2017

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Macaca
Visual Cortex
Neurons
Sensory Receptor Cells
Haplorhini
Decision Making

Keywords

  • Choice probability
  • Decision-making
  • V1
  • V2

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Dissociation of choice formation and choice-correlated activity in macaque visual cortex. / Goris, Robbe L.T.; Ziemba, Corey M.; Stine, Gabriel M.; Simoncelli, Eero; Movshon, J. Anthony.

In: Journal of Neuroscience, Vol. 37, No. 20, 17.05.2017, p. 5195-5203.

Research output: Contribution to journalArticle

Goris, Robbe L.T. ; Ziemba, Corey M. ; Stine, Gabriel M. ; Simoncelli, Eero ; Movshon, J. Anthony. / Dissociation of choice formation and choice-correlated activity in macaque visual cortex. In: Journal of Neuroscience. 2017 ; Vol. 37, No. 20. pp. 5195-5203.
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