Dissecting neural circuits for multisensory integration and crossmodal processing

Jeffrey M. Yau, Gregory C. DeAngelis, Dora Angelaki

Research output: Contribution to journalReview article

Abstract

We rely on rich and complex sensory information to perceive and understand our environment. Our multisensory experience of the world depends on the brain’s remarkable ability to combine signals across sensory systems. Behavioural, neurophysiological and neuroimaging experiments have established principles of multisensory integration and candidate neural mechanisms. Here we review how targeted manipulation of neural activity using invasive and non-invasive neuromodulation techniques have advanced our understanding of multisensory processing. Neuromodulation studies have provided detailed characterizations of brain networks causally involved in multisensory integration. Despite substantial progress, important questions regarding multisensory networks remain unanswered. Critically, experimental approaches will need to be combined with theory in order to understand howdistributed activity across multisensory networks collectively supports perception.

Original languageEnglish (US)
Article number20140203
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume370
Issue number1677
DOIs
StatePublished - Sep 19 2015

Fingerprint

Brain
Neuroimaging
brain
sensory system
Aptitude
Networks (circuits)
Processing
Experiments
methodology

Keywords

  • Causal
  • Interactions
  • Microstimulation
  • Modulation
  • Network
  • Perception

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Dissecting neural circuits for multisensory integration and crossmodal processing. / Yau, Jeffrey M.; DeAngelis, Gregory C.; Angelaki, Dora.

In: Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 370, No. 1677, 20140203, 19.09.2015.

Research output: Contribution to journalReview article

@article{4a1348cabbd44ee2a9fd319ed4278b20,
title = "Dissecting neural circuits for multisensory integration and crossmodal processing",
abstract = "We rely on rich and complex sensory information to perceive and understand our environment. Our multisensory experience of the world depends on the brain’s remarkable ability to combine signals across sensory systems. Behavioural, neurophysiological and neuroimaging experiments have established principles of multisensory integration and candidate neural mechanisms. Here we review how targeted manipulation of neural activity using invasive and non-invasive neuromodulation techniques have advanced our understanding of multisensory processing. Neuromodulation studies have provided detailed characterizations of brain networks causally involved in multisensory integration. Despite substantial progress, important questions regarding multisensory networks remain unanswered. Critically, experimental approaches will need to be combined with theory in order to understand howdistributed activity across multisensory networks collectively supports perception.",
keywords = "Causal, Interactions, Microstimulation, Modulation, Network, Perception",
author = "Yau, {Jeffrey M.} and DeAngelis, {Gregory C.} and Dora Angelaki",
year = "2015",
month = "9",
day = "19",
doi = "10.1098/rstb.2014.0203",
language = "English (US)",
volume = "370",
journal = "Philosophical Transactions of the Royal Society B: Biological Sciences",
issn = "0962-8436",
publisher = "Royal Society of London",
number = "1677",

}

TY - JOUR

T1 - Dissecting neural circuits for multisensory integration and crossmodal processing

AU - Yau, Jeffrey M.

AU - DeAngelis, Gregory C.

AU - Angelaki, Dora

PY - 2015/9/19

Y1 - 2015/9/19

N2 - We rely on rich and complex sensory information to perceive and understand our environment. Our multisensory experience of the world depends on the brain’s remarkable ability to combine signals across sensory systems. Behavioural, neurophysiological and neuroimaging experiments have established principles of multisensory integration and candidate neural mechanisms. Here we review how targeted manipulation of neural activity using invasive and non-invasive neuromodulation techniques have advanced our understanding of multisensory processing. Neuromodulation studies have provided detailed characterizations of brain networks causally involved in multisensory integration. Despite substantial progress, important questions regarding multisensory networks remain unanswered. Critically, experimental approaches will need to be combined with theory in order to understand howdistributed activity across multisensory networks collectively supports perception.

AB - We rely on rich and complex sensory information to perceive and understand our environment. Our multisensory experience of the world depends on the brain’s remarkable ability to combine signals across sensory systems. Behavioural, neurophysiological and neuroimaging experiments have established principles of multisensory integration and candidate neural mechanisms. Here we review how targeted manipulation of neural activity using invasive and non-invasive neuromodulation techniques have advanced our understanding of multisensory processing. Neuromodulation studies have provided detailed characterizations of brain networks causally involved in multisensory integration. Despite substantial progress, important questions regarding multisensory networks remain unanswered. Critically, experimental approaches will need to be combined with theory in order to understand howdistributed activity across multisensory networks collectively supports perception.

KW - Causal

KW - Interactions

KW - Microstimulation

KW - Modulation

KW - Network

KW - Perception

UR - http://www.scopus.com/inward/record.url?scp=84938535534&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938535534&partnerID=8YFLogxK

U2 - 10.1098/rstb.2014.0203

DO - 10.1098/rstb.2014.0203

M3 - Review article

VL - 370

JO - Philosophical Transactions of the Royal Society B: Biological Sciences

JF - Philosophical Transactions of the Royal Society B: Biological Sciences

SN - 0962-8436

IS - 1677

M1 - 20140203

ER -