Discrimination between hard metals with soft ligand donor atoms: An on-fluorescence probe for manganese(II)

Jian Liang, James W. Canary

Research output: Contribution to journalArticle

Abstract

A backwards strategy for achieving Mn2+/Ca2+ selectivity was demonstrated: Instead of optimizing binding of Mn2+, the bapta ligand (upper structure in scheme) was modified by changing O to N donors to discourage association by unwanted competitor Ca2+. Attachment of a fluorophore gave a Mn2+- selective on-fluorescent probe for use in live cell imaging.

Original languageEnglish (US)
Pages (from-to)7710-7713
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number42
DOIs
StatePublished - Oct 11 2010

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Keywords

  • Calcium
  • Cellular imaging
  • Coordination chemistry
  • Fluorescence
  • Manganese

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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