Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys

Stephane Boissinot, Christian Roos, Anthony V. Furano

    Research output: Contribution to journalArticle

    Abstract

    LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamarin (Saguinus oedipus), and the spider monkey (Ateles paniscus). Since these three species diverged, L1 has amplified in the Saimiri and Saguinus lineages but L1 activity seems to have been strongly reduced in the Ateles lineage. In addition, the active L1 lineage has evolved rapidly in Saimiri and Saguinus, generating species-specific subfamilies. In contrast, we found no evidence for a species-specific subfamily in Ateles, a result consistent with the low L1 activity in this species for the last ∼25 My.

    Original languageEnglish (US)
    Pages (from-to)122-130
    Number of pages9
    JournalJournal of Molecular Evolution
    Volume58
    Issue number1
    DOIs
    StatePublished - Jan 1 2004

    Fingerprint

    Atelinae
    Platyrrhini
    Ateles
    Saimiri
    Cebidae
    Retroelements
    Saguinus
    retrotransposons
    amplification
    Saguinus oedipus
    Saimiri sciureus
    Long Interspersed Nucleotide Elements
    Callitrichidae
    monkeys
    Araneae
    open reading frames
    Open Reading Frames
    genome
    spider
    Genome

    Keywords

    • LINE-1
    • New World monkeys
    • Non-LTR
    • Primate
    • Retrotransposon

    ASJC Scopus subject areas

    • Ecology, Evolution, Behavior and Systematics
    • Molecular Biology
    • Genetics

    Cite this

    Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys. / Boissinot, Stephane; Roos, Christian; Furano, Anthony V.

    In: Journal of Molecular Evolution, Vol. 58, No. 1, 01.01.2004, p. 122-130.

    Research output: Contribution to journalArticle

    Boissinot, Stephane ; Roos, Christian ; Furano, Anthony V. / Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys. In: Journal of Molecular Evolution. 2004 ; Vol. 58, No. 1. pp. 122-130.
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