Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys

Stephane Boissinot, Christian Roos, Anthony V. Furano

Research output: Contribution to journalArticle

Abstract

LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamarin (Saguinus oedipus), and the spider monkey (Ateles paniscus). Since these three species diverged, L1 has amplified in the Saimiri and Saguinus lineages but L1 activity seems to have been strongly reduced in the Ateles lineage. In addition, the active L1 lineage has evolved rapidly in Saimiri and Saguinus, generating species-specific subfamilies. In contrast, we found no evidence for a species-specific subfamily in Ateles, a result consistent with the low L1 activity in this species for the last ∼25 My.

Original languageEnglish (US)
Pages (from-to)122-130
Number of pages9
JournalJournal of Molecular Evolution
Volume58
Issue number1
DOIs
StatePublished - Jan 1 2004

Fingerprint

Atelinae
Platyrrhini
Ateles
Saimiri
Cebidae
Retroelements
Saguinus
retrotransposons
amplification
Saguinus oedipus
Saimiri sciureus
Long Interspersed Nucleotide Elements
Callitrichidae
monkeys
Araneae
open reading frames
Open Reading Frames
genome
spider
Genome

Keywords

  • LINE-1
  • New World monkeys
  • Non-LTR
  • Primate
  • Retrotransposon

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Cite this

Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys. / Boissinot, Stephane; Roos, Christian; Furano, Anthony V.

In: Journal of Molecular Evolution, Vol. 58, No. 1, 01.01.2004, p. 122-130.

Research output: Contribution to journalArticle

@article{ef09ed10b59c46a19c3aeeb09f810526,
title = "Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys",
abstract = "LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamarin (Saguinus oedipus), and the spider monkey (Ateles paniscus). Since these three species diverged, L1 has amplified in the Saimiri and Saguinus lineages but L1 activity seems to have been strongly reduced in the Ateles lineage. In addition, the active L1 lineage has evolved rapidly in Saimiri and Saguinus, generating species-specific subfamilies. In contrast, we found no evidence for a species-specific subfamily in Ateles, a result consistent with the low L1 activity in this species for the last ∼25 My.",
keywords = "LINE-1, New World monkeys, Non-LTR, Primate, Retrotransposon",
author = "Stephane Boissinot and Christian Roos and Furano, {Anthony V.}",
year = "2004",
month = "1",
day = "1",
doi = "10.1007/s00239-003-2539-x",
language = "English (US)",
volume = "58",
pages = "122--130",
journal = "Journal of Molecular Evolution",
issn = "0022-2844",
publisher = "Springer New York",
number = "1",

}

TY - JOUR

T1 - Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys

AU - Boissinot, Stephane

AU - Roos, Christian

AU - Furano, Anthony V.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamarin (Saguinus oedipus), and the spider monkey (Ateles paniscus). Since these three species diverged, L1 has amplified in the Saimiri and Saguinus lineages but L1 activity seems to have been strongly reduced in the Ateles lineage. In addition, the active L1 lineage has evolved rapidly in Saimiri and Saguinus, generating species-specific subfamilies. In contrast, we found no evidence for a species-specific subfamily in Ateles, a result consistent with the low L1 activity in this species for the last ∼25 My.

AB - LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamarin (Saguinus oedipus), and the spider monkey (Ateles paniscus). Since these three species diverged, L1 has amplified in the Saimiri and Saguinus lineages but L1 activity seems to have been strongly reduced in the Ateles lineage. In addition, the active L1 lineage has evolved rapidly in Saimiri and Saguinus, generating species-specific subfamilies. In contrast, we found no evidence for a species-specific subfamily in Ateles, a result consistent with the low L1 activity in this species for the last ∼25 My.

KW - LINE-1

KW - New World monkeys

KW - Non-LTR

KW - Primate

KW - Retrotransposon

UR - http://www.scopus.com/inward/record.url?scp=1642544094&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1642544094&partnerID=8YFLogxK

U2 - 10.1007/s00239-003-2539-x

DO - 10.1007/s00239-003-2539-x

M3 - Article

C2 - 14743320

AN - SCOPUS:1642544094

VL - 58

SP - 122

EP - 130

JO - Journal of Molecular Evolution

JF - Journal of Molecular Evolution

SN - 0022-2844

IS - 1

ER -