Developmental shifts in fMRI activations during visuospatial relational reasoning

Paul J. Eslinger, Clancy Blair, JianLi Wang, Bryn Lipovsky, Jennifer Realmuto, David Baker, Steven Thorne, David Gamson, Erin Zimmerman, Lisa Rohrer, Qing X. Yang

Research output: Contribution to journalArticle

Abstract

To investigate maturational plasticity of fluid cognition systems, functional brain imaging was undertaken in healthy 8-19 year old participants while completing visuospatial relational reasoning problems similar to Raven's matrices and current elementary grade math textbooks. Analyses revealed that visuospatial relational reasoning across this developmental age range recruited activations in the superior parietal cortices most prominently, the dorsolateral prefrontal, occipital-temporal, and premotor/supplementary cortices, the basal ganglia, and insula. There were comparable activity volumes in left and right hemispheres for nearly all of these regions. Regression analyses indicated increasing activity predominantly in the superior parietal lobes with developmental age. In contrast, multiple anterior neural systems showed significantly less activity with age, including dorsolateral and ventrolateral prefrontal, paracentral, and insula cortices bilaterally, basal ganglia, and particularly large clusters in the midline anterior cingulate/medial frontal cortex, left middle cingulate/supplementary motor cortex, left insula-putamen, and left caudate. Findings suggest that neuromaturational changes associated with visuospatial relational reasoning shift from a more widespread fronto-cingulate-striatal pattern in childhood to predominant parieto-frontal activation pattern in late adolescence.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalBrain and Cognition
Volume69
Issue number1
DOIs
StatePublished - Feb 2009

Fingerprint

Parietal Lobe
Motor Cortex
Basal Ganglia
Magnetic Resonance Imaging
Corpus Striatum
Crows
Functional Neuroimaging
Textbooks
Putamen
Gyrus Cinguli
Frontal Lobe
Cognition
Regression Analysis
Cortex
Functional Magnetic Resonance Imaging
Activation
Insula

Keywords

  • Basal ganglia
  • Developmental brain imaging
  • Fluid intelligence
  • fMRI
  • Frontal lobe
  • Functional brain imaging
  • Parietal lobe
  • Relational reasoning
  • Visuospatial problem solving

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Eslinger, P. J., Blair, C., Wang, J., Lipovsky, B., Realmuto, J., Baker, D., ... Yang, Q. X. (2009). Developmental shifts in fMRI activations during visuospatial relational reasoning. Brain and Cognition, 69(1), 1-10. https://doi.org/10.1016/j.bandc.2008.04.010

Developmental shifts in fMRI activations during visuospatial relational reasoning. / Eslinger, Paul J.; Blair, Clancy; Wang, JianLi; Lipovsky, Bryn; Realmuto, Jennifer; Baker, David; Thorne, Steven; Gamson, David; Zimmerman, Erin; Rohrer, Lisa; Yang, Qing X.

In: Brain and Cognition, Vol. 69, No. 1, 02.2009, p. 1-10.

Research output: Contribution to journalArticle

Eslinger, PJ, Blair, C, Wang, J, Lipovsky, B, Realmuto, J, Baker, D, Thorne, S, Gamson, D, Zimmerman, E, Rohrer, L & Yang, QX 2009, 'Developmental shifts in fMRI activations during visuospatial relational reasoning', Brain and Cognition, vol. 69, no. 1, pp. 1-10. https://doi.org/10.1016/j.bandc.2008.04.010
Eslinger, Paul J. ; Blair, Clancy ; Wang, JianLi ; Lipovsky, Bryn ; Realmuto, Jennifer ; Baker, David ; Thorne, Steven ; Gamson, David ; Zimmerman, Erin ; Rohrer, Lisa ; Yang, Qing X. / Developmental shifts in fMRI activations during visuospatial relational reasoning. In: Brain and Cognition. 2009 ; Vol. 69, No. 1. pp. 1-10.
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