Designing polymers that mimic biomolecules

Kent Kirshenbaum, Ronald N. Zuckermann, Ken A. Dill

Research output: Contribution to journalArticle

Abstract

A new field is emerging. Chemists are beginning to synthesize polymers with properties that are similar to those of proteins and RNA. Recent studies have identified oligomer backbones that form stable secondary structures. It is now possible to assemble specific sequences of diverse monomer sets into chain lengths that are nearly sufficient for tertiary structure formation. Such molecules will teach us how natural biopolymers fold; they will also enable us to design synthetic heteropolymers with novel structures and desirable functions.

Original languageEnglish (US)
Pages (from-to)530-535
Number of pages6
JournalCurrent Opinion in Structural Biology
Volume9
Issue number4
DOIs
StatePublished - Aug 1999

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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