Designed molecular switches: Controlling the conformation of benzamido-diphenylacetylenes

Ian M. Jones, Andrew Hamilton

Research output: Contribution to journalArticle

Abstract

With the goal of creating a molecular switch, the hydrogen-bonded diphenylacetylene structure has been modified such that an equilibrium now exists between two intramolecular H-bonded states. Through X-ray crystallography and 1H NMR analysis it is shown that this equilibrium can be biased in a predictable manner by modulating the relative acidity of the amide NH's.

Original languageEnglish (US)
Pages (from-to)3651-3653
Number of pages3
JournalOrganic Letters
Volume12
Issue number16
DOIs
StatePublished - Aug 20 2010

Fingerprint

X ray crystallography
X Ray Crystallography
Acidity
Amides
Conformations
Hydrogen
switches
Switches
Nuclear magnetic resonance
acidity
amides
crystallography
nuclear magnetic resonance
hydrogen
x rays
biphenylacetylene
Proton Magnetic Resonance Spectroscopy

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Designed molecular switches : Controlling the conformation of benzamido-diphenylacetylenes. / Jones, Ian M.; Hamilton, Andrew.

In: Organic Letters, Vol. 12, No. 16, 20.08.2010, p. 3651-3653.

Research output: Contribution to journalArticle

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