Depressive symptoms and their association with social determinants and chronic diseases in middle-aged and elderly Chinese people

Qiaolan Liu, Hui Cai, Lawrence H. Yang, Yong Bing Xiang, Gong Yang, Honglan Li, Yu Tang Gao, Wei Zheng, Ezra Susser, Xiao Ou Shu

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Depression is one of the most prevalent mental disorders worldwide. Little information is available regarding association of depressive symptoms (DS) with cancer and chronic diseases among middle-aged and elderly Chinese in a population-based setting. In this study we evaluated the prevalence and examined correlates of DS in two population-based cohort studies. Included in the analyses were 103,595 people with a mean age of 61.8 years at the DS assessment. The prevalence of DS was 2.4% in men and 5.6% in women. We found elderly participants, those with lower BMI, or chronic diseases were more likely to experience DS. Having a history of stroke (odds ratio (OR) = 2.2 in men and 1.8 in women), cancer (OR = 3.3 in men and 1.9 in women), or Parkinson's disease (OR = 3.1 in men and 2.7 in women) was associated with high DS. In women, high income and high education levels were inversely related to DS. Being a single woman, long-term or heavy female smoker was associated with high prevalence of DS. High BMI was correlated with low prevalence of depression in men. Our data suggests a low prevalence of DS among middle-aged and elderly people in Shanghai, China. Age, education, income, marital status, smoking, BMI, and certain health conditions were associated with DS.

Original languageEnglish (US)
Article number3841
JournalScientific reports
Issue number1
StatePublished - Dec 1 2018


ASJC Scopus subject areas

  • General

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