Dehydration in black and white older adults using diuretics

Kristie Lancaster, Helen Smiciklas-Wright, Debra A. Heller, Frank M. Ahern, Gordon Jensen

Research output: Contribution to journalArticle

Abstract

PURPOSE: To assess the association between dehydration and ethnicity in older adults; and to determine if diuretic use can help explain the disparity between blacks and whites in diagnosis of dehydration. METHODS: We conducted a case-control study in black and white older adults in a pharmaceutical assistance program who were hospitalized during 1997. Cases were all those diagnosed with dehydration (N = 9,186). Randomly selected controls were 4:1 frequency matched to cases by sex and age group (NTotal = 45,585). RESULTS: Patients taking loop, potassium-sparing, thiazide or combination diuretics were more likely to have a diagnosis of dehydration. Dehydration diagnosis was associated with being black (odds ratio (OR) = 1.49, 95% confidence interval (CI), 1.36-1.63, p<.001), independent of diuretic use or dosage. That association remained when examining loop (OR = 1.36, 95% CI, 1.10-1.63, p<.004) and thiazide diuretic users (OR = 1.59, 95% CI, 1.09-2.34, p = .017), but not potassium-sparing or combination diuretic users. CONCLUSION: Diuretic use is significantly associated with dehydration diagnosis, but the greater likelihood of older blacks being diagnosed with dehydration is independent of diuretic use. The increased risk of morbidity and mortality associated with dehydration suggests that further examination of the root cause of this disparity in risk is warranted.

Original languageEnglish (US)
Pages (from-to)525-529
Number of pages5
JournalAnnals of Epidemiology
Volume13
Issue number7
DOIs
StatePublished - Aug 2003

Fingerprint

Dehydration
Diuretics
Odds Ratio
Confidence Intervals
Potassium
Thiazides
Sodium Chloride Symporter Inhibitors
hydroquinone
Case-Control Studies
Age Groups
Morbidity
Mortality
Pharmaceutical Preparations

Keywords

  • Blacks
  • Case-Control Studies
  • Dehydration
  • Diuretics
  • Ethnicity

ASJC Scopus subject areas

  • Medicine(all)
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Lancaster, K., Smiciklas-Wright, H., Heller, D. A., Ahern, F. M., & Jensen, G. (2003). Dehydration in black and white older adults using diuretics. Annals of Epidemiology, 13(7), 525-529. https://doi.org/10.1016/S1047-2797(03)00004-8

Dehydration in black and white older adults using diuretics. / Lancaster, Kristie; Smiciklas-Wright, Helen; Heller, Debra A.; Ahern, Frank M.; Jensen, Gordon.

In: Annals of Epidemiology, Vol. 13, No. 7, 08.2003, p. 525-529.

Research output: Contribution to journalArticle

Lancaster, K, Smiciklas-Wright, H, Heller, DA, Ahern, FM & Jensen, G 2003, 'Dehydration in black and white older adults using diuretics', Annals of Epidemiology, vol. 13, no. 7, pp. 525-529. https://doi.org/10.1016/S1047-2797(03)00004-8
Lancaster, Kristie ; Smiciklas-Wright, Helen ; Heller, Debra A. ; Ahern, Frank M. ; Jensen, Gordon. / Dehydration in black and white older adults using diuretics. In: Annals of Epidemiology. 2003 ; Vol. 13, No. 7. pp. 525-529.
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