Decoding modulation of the neuromuscular transform

Estee Stern, Timothy J. Fort, Mark W. Miller, Charles Peskin, Vladimir Brezina

Research output: Contribution to journalArticle

Abstract

When modulators of neuromuscular function alter the motor neuron spike patterns that elicit muscle contractions, it is predicted that they will also retune correspondingly the connecting processes of the neuromuscular transform. Here we confirm this prediction by analyzing data from the cardiac neuromuscular system of the blue crab. We apply a method that decodes the contraction response to the spike pattern in terms of three elementary building-block functions that completely characterize the neuromuscular transform. This method allows us to dissociate modulator-induced changes in the neuromuscular transform from changes in the spike pattern in the normally operating, essentially unperturbed neuromuscular system.

Original languageEnglish (US)
Pages (from-to)1753-1758
Number of pages6
JournalNeurocomputing
Volume70
Issue number10-12
DOIs
StatePublished - Jun 2007

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Modulators
Decoding
Modulation
Brachyura
Motor Neurons
Muscle Contraction
Neurons
Muscle

Keywords

  • Neuromodulation
  • Neuromuscular system
  • Reconstruction
  • Spike train
  • Stimulus-response decoding

ASJC Scopus subject areas

  • Artificial Intelligence
  • Cellular and Molecular Neuroscience

Cite this

Stern, E., Fort, T. J., Miller, M. W., Peskin, C., & Brezina, V. (2007). Decoding modulation of the neuromuscular transform. Neurocomputing, 70(10-12), 1753-1758. https://doi.org/10.1016/j.neucom.2006.10.117

Decoding modulation of the neuromuscular transform. / Stern, Estee; Fort, Timothy J.; Miller, Mark W.; Peskin, Charles; Brezina, Vladimir.

In: Neurocomputing, Vol. 70, No. 10-12, 06.2007, p. 1753-1758.

Research output: Contribution to journalArticle

Stern, E, Fort, TJ, Miller, MW, Peskin, C & Brezina, V 2007, 'Decoding modulation of the neuromuscular transform', Neurocomputing, vol. 70, no. 10-12, pp. 1753-1758. https://doi.org/10.1016/j.neucom.2006.10.117
Stern E, Fort TJ, Miller MW, Peskin C, Brezina V. Decoding modulation of the neuromuscular transform. Neurocomputing. 2007 Jun;70(10-12):1753-1758. https://doi.org/10.1016/j.neucom.2006.10.117
Stern, Estee ; Fort, Timothy J. ; Miller, Mark W. ; Peskin, Charles ; Brezina, Vladimir. / Decoding modulation of the neuromuscular transform. In: Neurocomputing. 2007 ; Vol. 70, No. 10-12. pp. 1753-1758.
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