Abstract
Decision making has recently emerged as a central theme in neurophysiological studies of cognition, and experimental and computational work has led to the proposal of a cortical circuit mechanism of elemental decision computations. This mechanism depends on slow recurrent synaptic excitation balanced by fast feedback inhibition, which not only instantiates attractor states for forming categorical choices but also long transients for gradually accumulating evidence in favor of or against alternative options. Such a circuit endowed with reward-dependent synaptic plasticity is able to produce adaptive choice behavior. While decision threshold is a core concept for reaction time tasks, it can be dissociated from a general decision rule. Moreover, perceptual decisions and value-based economic choices are described within a unified framework in which probabilistic choices result from irregular neuronal activity as well as iterative interactions of a decision maker with an uncertain environment or other unpredictable decision makers in a social group.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 215-234 |
| Number of pages | 20 |
| Journal | Neuron |
| Volume | 60 |
| Issue number | 2 |
| DOIs | |
| State | Published - Oct 23 2008 |
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ASJC Scopus subject areas
- Neuroscience(all)
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Decision Making in Recurrent Neuronal Circuits. / Wang, Xiao-Jing.
In: Neuron, Vol. 60, No. 2, 23.10.2008, p. 215-234.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Decision Making in Recurrent Neuronal Circuits
AU - Wang, Xiao-Jing
PY - 2008/10/23
Y1 - 2008/10/23
N2 - Decision making has recently emerged as a central theme in neurophysiological studies of cognition, and experimental and computational work has led to the proposal of a cortical circuit mechanism of elemental decision computations. This mechanism depends on slow recurrent synaptic excitation balanced by fast feedback inhibition, which not only instantiates attractor states for forming categorical choices but also long transients for gradually accumulating evidence in favor of or against alternative options. Such a circuit endowed with reward-dependent synaptic plasticity is able to produce adaptive choice behavior. While decision threshold is a core concept for reaction time tasks, it can be dissociated from a general decision rule. Moreover, perceptual decisions and value-based economic choices are described within a unified framework in which probabilistic choices result from irregular neuronal activity as well as iterative interactions of a decision maker with an uncertain environment or other unpredictable decision makers in a social group.
AB - Decision making has recently emerged as a central theme in neurophysiological studies of cognition, and experimental and computational work has led to the proposal of a cortical circuit mechanism of elemental decision computations. This mechanism depends on slow recurrent synaptic excitation balanced by fast feedback inhibition, which not only instantiates attractor states for forming categorical choices but also long transients for gradually accumulating evidence in favor of or against alternative options. Such a circuit endowed with reward-dependent synaptic plasticity is able to produce adaptive choice behavior. While decision threshold is a core concept for reaction time tasks, it can be dissociated from a general decision rule. Moreover, perceptual decisions and value-based economic choices are described within a unified framework in which probabilistic choices result from irregular neuronal activity as well as iterative interactions of a decision maker with an uncertain environment or other unpredictable decision makers in a social group.
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U2 - 10.1016/j.neuron.2008.09.034
DO - 10.1016/j.neuron.2008.09.034
M3 - Article
VL - 60
SP - 215
EP - 234
JO - Neuron
JF - Neuron
SN - 0896-6273
IS - 2
ER -