Current development of saliva/oral fluid-based diagnostics.

Chih Ko Yeh, Nicolaos J. Christodoulides, Pierre N. Floriano, Craig S. Miller, Jeffrey L. Ebersole, Shannon E. Weigum, John McDevitt, Spencer W. Redding

Research output: Contribution to journalArticle

Abstract

Saliva can be easily obtained in medical and non-medical settings, and contains numerous bio-molecules, including those typically found in serum for disease detection and monitoring. In the past two decades, the achievements of high-throughput approaches afforded by biotechnology and nanotechnology allow for disease-specific salivary biomarker discovery and establishment of rapid, multiplex, and miniaturized analytical assays. These developments have dramatically advanced saliva-based diagnostics. In this review, we discuss the current consensus on development of saliva/oral fluid-based diagnostics and provide a summary of recent research advancements of the Texas-Kentucky Saliva Diagnostics Consortium. In the foreseeable future, current research on saliva based diagnostic methods could revolutionize health care.

Original languageEnglish (US)
Pages (from-to)651-661
Number of pages11
JournalTexas dental journal
Volume127
Issue number7
StatePublished - Jul 2010

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Saliva
Nanotechnology
Biotechnology
Research
Consensus
Biomarkers
Delivery of Health Care
Serum

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Yeh, C. K., Christodoulides, N. J., Floriano, P. N., Miller, C. S., Ebersole, J. L., Weigum, S. E., ... Redding, S. W. (2010). Current development of saliva/oral fluid-based diagnostics. Texas dental journal, 127(7), 651-661.

Current development of saliva/oral fluid-based diagnostics. / Yeh, Chih Ko; Christodoulides, Nicolaos J.; Floriano, Pierre N.; Miller, Craig S.; Ebersole, Jeffrey L.; Weigum, Shannon E.; McDevitt, John; Redding, Spencer W.

In: Texas dental journal, Vol. 127, No. 7, 07.2010, p. 651-661.

Research output: Contribution to journalArticle

Yeh, CK, Christodoulides, NJ, Floriano, PN, Miller, CS, Ebersole, JL, Weigum, SE, McDevitt, J & Redding, SW 2010, 'Current development of saliva/oral fluid-based diagnostics.', Texas dental journal, vol. 127, no. 7, pp. 651-661.
Yeh CK, Christodoulides NJ, Floriano PN, Miller CS, Ebersole JL, Weigum SE et al. Current development of saliva/oral fluid-based diagnostics. Texas dental journal. 2010 Jul;127(7):651-661.
Yeh, Chih Ko ; Christodoulides, Nicolaos J. ; Floriano, Pierre N. ; Miller, Craig S. ; Ebersole, Jeffrey L. ; Weigum, Shannon E. ; McDevitt, John ; Redding, Spencer W. / Current development of saliva/oral fluid-based diagnostics. In: Texas dental journal. 2010 ; Vol. 127, No. 7. pp. 651-661.
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