Crimped fiber with controllable patterns fabricated via electrohydrodynamic jet printing

Yang Wu, Bin Wu, Sanjairaj Vijayavenkataraman, Yoke San Wong, Jerry Ying Hsi Fuh

Research output: Contribution to journalArticle

Abstract

A regular pattern called crimp is an essential morphological feature of collagen fibers in native tendon. In this study, a crimped fiber writing process based on electrohydrodynamic jet printing (E-jetting) has been developed to fabricate fibers with crimped morphology. The effects of the key process parameters (i.e. segment length, stage speed and dwell time) on the fiber characteristics were investigated to obtain controllable and regular crimped fibers. The induced crimp angle (~ 15°) and fiber diameter (~ 45 μm) using the optimal process parameters were comparable to those in the native tendons (i.e. 13–17° and 15–30 μm, respectively). Mechanical testing showed that the crimped fibers exhibited an initial nonlinear region and a subsequent linear region with different Young's modulus (22.6 ± 2.2 MPa and 33.2 ± 6.5 MPa, respectively), while the straight fibers were found only with a linear region. Human tenocytes cultured on the crimped fibers exhibited the aligned morphology with a broader and controllable nuclei angle distribution, as compared to those on the straight fibers. This study indicates the capability of crimped fiber writing to create fibers with controllable crimped morphology and biomimetic mechanical behaviors, demonstrating its potential in application of tissue engineering.

Original languageEnglish (US)
Pages (from-to)384-393
Number of pages10
JournalMaterials and Design
Volume131
DOIs
StatePublished - Oct 5 2017

Fingerprint

Electrohydrodynamics
Printing
Fibers
Tendons
Mechanical testing
Bioelectric potentials
Biomimetics
Tissue engineering
Collagen
Elastic moduli

Keywords

  • Cell alignment
  • Crimp-like pattern
  • Electrohydrodynamic jet printing
  • Tissue engineering

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Crimped fiber with controllable patterns fabricated via electrohydrodynamic jet printing. / Wu, Yang; Wu, Bin; Vijayavenkataraman, Sanjairaj; Wong, Yoke San; Fuh, Jerry Ying Hsi.

In: Materials and Design, Vol. 131, 05.10.2017, p. 384-393.

Research output: Contribution to journalArticle

Wu, Yang ; Wu, Bin ; Vijayavenkataraman, Sanjairaj ; Wong, Yoke San ; Fuh, Jerry Ying Hsi. / Crimped fiber with controllable patterns fabricated via electrohydrodynamic jet printing. In: Materials and Design. 2017 ; Vol. 131. pp. 384-393.
@article{02334ebff12645a096d558b78634f68f,
title = "Crimped fiber with controllable patterns fabricated via electrohydrodynamic jet printing",
abstract = "A regular pattern called crimp is an essential morphological feature of collagen fibers in native tendon. In this study, a crimped fiber writing process based on electrohydrodynamic jet printing (E-jetting) has been developed to fabricate fibers with crimped morphology. The effects of the key process parameters (i.e. segment length, stage speed and dwell time) on the fiber characteristics were investigated to obtain controllable and regular crimped fibers. The induced crimp angle (~ 15°) and fiber diameter (~ 45 μm) using the optimal process parameters were comparable to those in the native tendons (i.e. 13–17° and 15–30 μm, respectively). Mechanical testing showed that the crimped fibers exhibited an initial nonlinear region and a subsequent linear region with different Young's modulus (22.6 ± 2.2 MPa and 33.2 ± 6.5 MPa, respectively), while the straight fibers were found only with a linear region. Human tenocytes cultured on the crimped fibers exhibited the aligned morphology with a broader and controllable nuclei angle distribution, as compared to those on the straight fibers. This study indicates the capability of crimped fiber writing to create fibers with controllable crimped morphology and biomimetic mechanical behaviors, demonstrating its potential in application of tissue engineering.",
keywords = "Cell alignment, Crimp-like pattern, Electrohydrodynamic jet printing, Tissue engineering",
author = "Yang Wu and Bin Wu and Sanjairaj Vijayavenkataraman and Wong, {Yoke San} and Fuh, {Jerry Ying Hsi}",
year = "2017",
month = "10",
day = "5",
doi = "10.1016/j.matdes.2017.06.027",
language = "English (US)",
volume = "131",
pages = "384--393",
journal = "Materials and Design",
issn = "0264-1275",
publisher = "Elsevier BV",

}

TY - JOUR

T1 - Crimped fiber with controllable patterns fabricated via electrohydrodynamic jet printing

AU - Wu, Yang

AU - Wu, Bin

AU - Vijayavenkataraman, Sanjairaj

AU - Wong, Yoke San

AU - Fuh, Jerry Ying Hsi

PY - 2017/10/5

Y1 - 2017/10/5

N2 - A regular pattern called crimp is an essential morphological feature of collagen fibers in native tendon. In this study, a crimped fiber writing process based on electrohydrodynamic jet printing (E-jetting) has been developed to fabricate fibers with crimped morphology. The effects of the key process parameters (i.e. segment length, stage speed and dwell time) on the fiber characteristics were investigated to obtain controllable and regular crimped fibers. The induced crimp angle (~ 15°) and fiber diameter (~ 45 μm) using the optimal process parameters were comparable to those in the native tendons (i.e. 13–17° and 15–30 μm, respectively). Mechanical testing showed that the crimped fibers exhibited an initial nonlinear region and a subsequent linear region with different Young's modulus (22.6 ± 2.2 MPa and 33.2 ± 6.5 MPa, respectively), while the straight fibers were found only with a linear region. Human tenocytes cultured on the crimped fibers exhibited the aligned morphology with a broader and controllable nuclei angle distribution, as compared to those on the straight fibers. This study indicates the capability of crimped fiber writing to create fibers with controllable crimped morphology and biomimetic mechanical behaviors, demonstrating its potential in application of tissue engineering.

AB - A regular pattern called crimp is an essential morphological feature of collagen fibers in native tendon. In this study, a crimped fiber writing process based on electrohydrodynamic jet printing (E-jetting) has been developed to fabricate fibers with crimped morphology. The effects of the key process parameters (i.e. segment length, stage speed and dwell time) on the fiber characteristics were investigated to obtain controllable and regular crimped fibers. The induced crimp angle (~ 15°) and fiber diameter (~ 45 μm) using the optimal process parameters were comparable to those in the native tendons (i.e. 13–17° and 15–30 μm, respectively). Mechanical testing showed that the crimped fibers exhibited an initial nonlinear region and a subsequent linear region with different Young's modulus (22.6 ± 2.2 MPa and 33.2 ± 6.5 MPa, respectively), while the straight fibers were found only with a linear region. Human tenocytes cultured on the crimped fibers exhibited the aligned morphology with a broader and controllable nuclei angle distribution, as compared to those on the straight fibers. This study indicates the capability of crimped fiber writing to create fibers with controllable crimped morphology and biomimetic mechanical behaviors, demonstrating its potential in application of tissue engineering.

KW - Cell alignment

KW - Crimp-like pattern

KW - Electrohydrodynamic jet printing

KW - Tissue engineering

UR - http://www.scopus.com/inward/record.url?scp=85021163727&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021163727&partnerID=8YFLogxK

U2 - 10.1016/j.matdes.2017.06.027

DO - 10.1016/j.matdes.2017.06.027

M3 - Article

AN - SCOPUS:85021163727

VL - 131

SP - 384

EP - 393

JO - Materials and Design

JF - Materials and Design

SN - 0264-1275

ER -