Correlates of incident trichomonas vaginalis infections among African American female adolescents

Andrea Swartzendruber, Jessica M. Sales, Jennifer L. Brown, Ralph DiClemente, Eve S. Rose

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Trichomonas vaginalis is the most common curable sexually transmitted infection associated with adverse reproductive health and pregnancy outcomes and may amplify HIV transmission. The objective was to identify correlates of incident T. vaginalis infections among African American adolescent girls. METHODS: Data were collected via audio computer-assisted self-interviews at baseline and every 6 months for 18 months from 701 African American girls (14-20 years) in an HIV prevention trial. At each assessment, self-collected vaginal swabs were assayed for T. vaginalis, Chlamydia trachomatis, and Neisseria gonorrhoeae. Generalized estimating equations assessed associations between incident T. vaginalis infection and sociodemographic characteristics, substance use, partner-level factors, sexual risk behaviors, douching, and other sexually transmitted infections. RESULTS: Of 605 (86.3%) participants who completed at least 1 follow-up assessment, an incident T. vaginalis infection was detected among 20.0% (n = 121). Factors associated with incident infection in adjusted analysis included the following: cigarette smoking (adjusted odds ratio [AOR], 1.66; 95% confidence interval [CI], 1.04-2.64), using alcohol on an increasing number of days in the past 3 months (AOR, 1.02; 95% CI, 1.00-1.04), acquisition of C. trachomatis (AOR, 2.27; 95% CI, 1.40-3.69) or N. gonorrhoeae (AOR, 5.71; 95% CI, 2.97-11.02), and T. vaginalis infection at the previous assessment (AOR, 3.16; 95% CI, 1.96-5.07). CONCLUSIONS: Incident T. vaginalis infections were common. Strategies to reduce infection rates among this population may include improving partner notification and treatment services. The benefits of rescreening, screening adolescents screened for or infected with C. trachomatis or N. gonorrhoeae, and associations between substance use and T. vaginalis acquisition warrant further investigation.

Original languageEnglish (US)
Pages (from-to)240-245
Number of pages6
JournalSexually Transmitted Diseases
Volume41
Issue number4
DOIs
StatePublished - Apr 1 2014

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Trichomonas Infections
Trichomonas vaginalis
African Americans
Odds Ratio
Confidence Intervals
Neisseria gonorrhoeae
Chlamydia trachomatis
Sexually Transmitted Diseases
HIV
Contact Tracing
Therapeutic Irrigation
Reproductive Health
Pregnancy Outcome
Risk-Taking
Infection
Sexual Behavior
Smoking
Alcohols
Interviews

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Correlates of incident trichomonas vaginalis infections among African American female adolescents. / Swartzendruber, Andrea; Sales, Jessica M.; Brown, Jennifer L.; DiClemente, Ralph; Rose, Eve S.

In: Sexually Transmitted Diseases, Vol. 41, No. 4, 01.04.2014, p. 240-245.

Research output: Contribution to journalArticle

Swartzendruber, Andrea ; Sales, Jessica M. ; Brown, Jennifer L. ; DiClemente, Ralph ; Rose, Eve S. / Correlates of incident trichomonas vaginalis infections among African American female adolescents. In: Sexually Transmitted Diseases. 2014 ; Vol. 41, No. 4. pp. 240-245.
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abstract = "BACKGROUND: Trichomonas vaginalis is the most common curable sexually transmitted infection associated with adverse reproductive health and pregnancy outcomes and may amplify HIV transmission. The objective was to identify correlates of incident T. vaginalis infections among African American adolescent girls. METHODS: Data were collected via audio computer-assisted self-interviews at baseline and every 6 months for 18 months from 701 African American girls (14-20 years) in an HIV prevention trial. At each assessment, self-collected vaginal swabs were assayed for T. vaginalis, Chlamydia trachomatis, and Neisseria gonorrhoeae. Generalized estimating equations assessed associations between incident T. vaginalis infection and sociodemographic characteristics, substance use, partner-level factors, sexual risk behaviors, douching, and other sexually transmitted infections. RESULTS: Of 605 (86.3{\%}) participants who completed at least 1 follow-up assessment, an incident T. vaginalis infection was detected among 20.0{\%} (n = 121). Factors associated with incident infection in adjusted analysis included the following: cigarette smoking (adjusted odds ratio [AOR], 1.66; 95{\%} confidence interval [CI], 1.04-2.64), using alcohol on an increasing number of days in the past 3 months (AOR, 1.02; 95{\%} CI, 1.00-1.04), acquisition of C. trachomatis (AOR, 2.27; 95{\%} CI, 1.40-3.69) or N. gonorrhoeae (AOR, 5.71; 95{\%} CI, 2.97-11.02), and T. vaginalis infection at the previous assessment (AOR, 3.16; 95{\%} CI, 1.96-5.07). CONCLUSIONS: Incident T. vaginalis infections were common. Strategies to reduce infection rates among this population may include improving partner notification and treatment services. The benefits of rescreening, screening adolescents screened for or infected with C. trachomatis or N. gonorrhoeae, and associations between substance use and T. vaginalis acquisition warrant further investigation.",
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