Control of DNA structure and topology: an overview

Nadrian Seeman, Yuwen Zhang, Shou Ming Du, Hui Wang, John E. Mueller, Yinli Wang, Bing Liu, Jing Qi, Junghuei Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The DNA molecule was observed to pose a potential in the control of structure on the nanoscale. This behaviour of the DNA structure paved the way for several investigations. In solution synthesis, stable branched DNA molecule allowing one to make stick-figures was used to construct a covalently closed DNA molecule whose helix axes have the connectivity of a cube. The solid-support-based methodology which is more effective than solution synthesis was used to construct a molecule whose helix axes have the connectivity of a truncated octahedron. Control of branching and braiding topology are observed in these systems.

Original languageEnglish (US)
Title of host publicationMaterials Research Society Symposium - Proceedings
PublisherMaterials Research Society
Pages57-66
Number of pages10
Volume351
StatePublished - 1994
EventProceedings of the 1994 MRS Symposium - San Francisco, CA, USA
Duration: Apr 4 1994Apr 8 1994

Other

OtherProceedings of the 1994 MRS Symposium
CitySan Francisco, CA, USA
Period4/4/944/8/94

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Seeman, N., Zhang, Y., Du, S. M., Wang, H., Mueller, J. E., Wang, Y., Liu, B., Qi, J., & Chen, J. (1994). Control of DNA structure and topology: an overview. In Materials Research Society Symposium - Proceedings (Vol. 351, pp. 57-66). Materials Research Society.