Contour integration in amblyopic monkeys

Petra Kozma, Lynne Kiorpes

Research output: Contribution to journalArticle

Abstract

Amblyopia is characterized by losses in a variety of aspects of spatial vision, such as acuity and contrast sensitivity. Our goal was to learn whether those basic spatial deficits lead to impaired global perceptual processing in strabismic and anisometropic amblyopia. This question is unresolved by the current human psychophysical literature. We studied contour integration and contrast sensitivity in amblyopic monkeys. We found deficient contour integration in anisometropic as well as strabismic amblyopic monkeys. Some animals showed poor contour integration in the fellow eye as well as in the amblyopic eye. Orientation jitter of the elements in the contour systematically decreased contour-detection ability for control and fellow eyes, but had less effect on amblyopic eyes. The deficits were not clearly related to basic losses in contrast sensitivity and acuity for either type of amblyopia. We conclude that abnormal contour integration in amblyopes reflects disruption of mechanisms that are different from those that determine acuity and contrast sensitivity, and are likely to be central to V1.

Original languageEnglish (US)
Pages (from-to)577-588
Number of pages12
JournalVisual Neuroscience
Volume20
Issue number5
DOIs
StatePublished - Sep 2003

Fingerprint

Contrast Sensitivity
Amblyopia
Haplorhini
Aptitude

Keywords

  • Amblyopia
  • Contour integration
  • Nonhuman primate

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Contour integration in amblyopic monkeys. / Kozma, Petra; Kiorpes, Lynne.

In: Visual Neuroscience, Vol. 20, No. 5, 09.2003, p. 577-588.

Research output: Contribution to journalArticle

Kozma, Petra ; Kiorpes, Lynne. / Contour integration in amblyopic monkeys. In: Visual Neuroscience. 2003 ; Vol. 20, No. 5. pp. 577-588.
@article{87b71292b735477aa8633dd8b181a7f5,
title = "Contour integration in amblyopic monkeys",
abstract = "Amblyopia is characterized by losses in a variety of aspects of spatial vision, such as acuity and contrast sensitivity. Our goal was to learn whether those basic spatial deficits lead to impaired global perceptual processing in strabismic and anisometropic amblyopia. This question is unresolved by the current human psychophysical literature. We studied contour integration and contrast sensitivity in amblyopic monkeys. We found deficient contour integration in anisometropic as well as strabismic amblyopic monkeys. Some animals showed poor contour integration in the fellow eye as well as in the amblyopic eye. Orientation jitter of the elements in the contour systematically decreased contour-detection ability for control and fellow eyes, but had less effect on amblyopic eyes. The deficits were not clearly related to basic losses in contrast sensitivity and acuity for either type of amblyopia. We conclude that abnormal contour integration in amblyopes reflects disruption of mechanisms that are different from those that determine acuity and contrast sensitivity, and are likely to be central to V1.",
keywords = "Amblyopia, Contour integration, Nonhuman primate",
author = "Petra Kozma and Lynne Kiorpes",
year = "2003",
month = "9",
doi = "10.1017/S0952523803205113",
language = "English (US)",
volume = "20",
pages = "577--588",
journal = "Visual Neuroscience",
issn = "0952-5238",
publisher = "Cambridge University Press",
number = "5",

}

TY - JOUR

T1 - Contour integration in amblyopic monkeys

AU - Kozma, Petra

AU - Kiorpes, Lynne

PY - 2003/9

Y1 - 2003/9

N2 - Amblyopia is characterized by losses in a variety of aspects of spatial vision, such as acuity and contrast sensitivity. Our goal was to learn whether those basic spatial deficits lead to impaired global perceptual processing in strabismic and anisometropic amblyopia. This question is unresolved by the current human psychophysical literature. We studied contour integration and contrast sensitivity in amblyopic monkeys. We found deficient contour integration in anisometropic as well as strabismic amblyopic monkeys. Some animals showed poor contour integration in the fellow eye as well as in the amblyopic eye. Orientation jitter of the elements in the contour systematically decreased contour-detection ability for control and fellow eyes, but had less effect on amblyopic eyes. The deficits were not clearly related to basic losses in contrast sensitivity and acuity for either type of amblyopia. We conclude that abnormal contour integration in amblyopes reflects disruption of mechanisms that are different from those that determine acuity and contrast sensitivity, and are likely to be central to V1.

AB - Amblyopia is characterized by losses in a variety of aspects of spatial vision, such as acuity and contrast sensitivity. Our goal was to learn whether those basic spatial deficits lead to impaired global perceptual processing in strabismic and anisometropic amblyopia. This question is unresolved by the current human psychophysical literature. We studied contour integration and contrast sensitivity in amblyopic monkeys. We found deficient contour integration in anisometropic as well as strabismic amblyopic monkeys. Some animals showed poor contour integration in the fellow eye as well as in the amblyopic eye. Orientation jitter of the elements in the contour systematically decreased contour-detection ability for control and fellow eyes, but had less effect on amblyopic eyes. The deficits were not clearly related to basic losses in contrast sensitivity and acuity for either type of amblyopia. We conclude that abnormal contour integration in amblyopes reflects disruption of mechanisms that are different from those that determine acuity and contrast sensitivity, and are likely to be central to V1.

KW - Amblyopia

KW - Contour integration

KW - Nonhuman primate

UR - http://www.scopus.com/inward/record.url?scp=1642360082&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1642360082&partnerID=8YFLogxK

U2 - 10.1017/S0952523803205113

DO - 10.1017/S0952523803205113

M3 - Article

VL - 20

SP - 577

EP - 588

JO - Visual Neuroscience

JF - Visual Neuroscience

SN - 0952-5238

IS - 5

ER -