Comprehensive imaging of cortical networks

Simon Peron, Tsai Wen Chen, Karel Svoboda

Research output: Contribution to journalReview article

Abstract

Neural computations are implemented by activity in spatially distributed neural circuits. Cellular imaging fills a unique niche in linking activity of specific types of neurons to behavior, over spatial scales spanning single neurons to entire brain regions, and temporal scales from milliseconds to months. Imaging may soon make it possible to track activity of all neurons in a brain region, such as a cortical column. We review recent methodological advances that facilitate optical imaging of neuronal populations in vivo, with an emphasis on calcium imaging using protein indicators in mice. We point out areas that are particularly ripe for future developments.

Original languageEnglish (US)
Pages (from-to)115-123
Number of pages9
JournalCurrent Opinion in Neurobiology
Volume32
DOIs
StatePublished - Jun 1 2015

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Neurons
Optical Imaging
Brain
Temporal Lobe
Calcium
Population
Proteins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Comprehensive imaging of cortical networks. / Peron, Simon; Chen, Tsai Wen; Svoboda, Karel.

In: Current Opinion in Neurobiology, Vol. 32, 01.06.2015, p. 115-123.

Research output: Contribution to journalReview article

Peron, Simon ; Chen, Tsai Wen ; Svoboda, Karel. / Comprehensive imaging of cortical networks. In: Current Opinion in Neurobiology. 2015 ; Vol. 32. pp. 115-123.
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