Compound stimulus extinction reduces spontaneous recovery in humans

Cesar A O Coelho, Joseph E. Dunsmoor, Elizabeth Phelps

Research output: Contribution to journalArticle

Abstract

Fear-related behaviors are prone to relapse following extinction. We tested in humans a compound extinction design ("deepened extinction") shown in animal studies to reduce post-extinction fear recovery. Adult subjects underwent fear conditioning to a visual and an auditory conditioned stimulus (CSA and CSB, respectively) separately paired with an electric shock. The target CS (CSA) was extinguished alone followed by compound presentations of the extinguished CSA and non-extinguished CSB. Recovery of conditioned skin conductance responses to CSA was reduced 24 h after compound extinction, as compared with a group who received an equal number of extinction trials to the CSA alone.

Original languageEnglish (US)
Pages (from-to)589-593
Number of pages5
JournalLearning and Memory
Volume22
Issue number12
DOIs
StatePublished - Dec 1 2015

Fingerprint

Fear
Psychological Extinction
Shock
Recurrence
Skin
Conditioning (Psychology)

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience
  • Neuropsychology and Physiological Psychology

Cite this

Compound stimulus extinction reduces spontaneous recovery in humans. / Coelho, Cesar A O; Dunsmoor, Joseph E.; Phelps, Elizabeth.

In: Learning and Memory, Vol. 22, No. 12, 01.12.2015, p. 589-593.

Research output: Contribution to journalArticle

Coelho, Cesar A O ; Dunsmoor, Joseph E. ; Phelps, Elizabeth. / Compound stimulus extinction reduces spontaneous recovery in humans. In: Learning and Memory. 2015 ; Vol. 22, No. 12. pp. 589-593.
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