Comparative in vitro study of 3D robocasting scaffolds using beta tricalcium phosphate and synthetic bone mineral

Cristobal Rivera, Lukasz Witek, Dindo Mijares, Ane Larranaga-Vega, Bruce N. Cronstein, Paulo G. Coelho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Introduction: Bone defects may occur due to various congenital disorders, traumas, tumors, or oncological resections. As a treatment option, bioactive ceramic-based graft materials have been used to regenerate bone1. One example of a bioceramic material used to regenerate bone is Synthetic Bone Mineral (SBM), which is described as a carbonate hydroxyapatite with ionic substitutions such as F-, Zn2+ and Mg2+. A novel formulation of SBM has been studied, showing successful results; improving bone density and promoting bone formation2. SBM colloidal gel has been fabricated for robocasting applications3. A robocasting 3D printer is used to customize ceramic structures for building scaffolds for bone regeneration4. The objective of this work is to compare the in vitro performance of printed 3D scaffolds made from two different bioceramic materials, β-tricalcium phosphate (β-TCP) and SBM.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

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ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

Cite this

Rivera, C., Witek, L., Mijares, D., Larranaga-Vega, A., Cronstein, B. N., & Coelho, P. G. (2019). Comparative in vitro study of 3D robocasting scaffolds using beta tricalcium phosphate and synthetic bone mineral. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.