COLLAGEN PRODUCTION BY RAT TENDON FIBROBLASTS CULTURED ON CARBON FILAMENT AND ON STANDARD CULTURE PLATES.

John Ricci, A. G. Gona, H. Alexander, J. R. Parsons

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A filamentous carbon absorbable polymer composite has been used as a tissue scaffold material for the repair of tendon and ligament trauma in both animals and man. As the polymer absorbs, tendon or ligament cells grow into the carbon fiber scaffold, orient parallel to the 8 mu m diameter fibers and produce new collagen. The resulting structure resembles normal tendon or ligament tissue both mechanically and histologically. This study is part of a series of in-vitro experiments designed to characterize rat tendon fibroblast (RTF) cell response to carbon fiber scaffold material. Studies of the growth rates of RTF cells cultured on carbon fiber indicated that substrate geometric configuration influenced cell growth rates**5. This study consists of duplicate experiments designed to examine the collagen synthesis rates of RTF cells cultured on carbon fiber substrates and on standard culture plates.

Original languageEnglish (US)
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the Interna
PublisherSoc for Biomaterials
Pages14
Number of pages1
Volume8
StatePublished - 1985

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Tendons
Fibroblasts
Cell culture
Collagen
Rats
Carbon fibers
Carbon
Ligaments
Scaffolds
Cell growth
Polymers
Substrates
Animals
Repair
Experiments
Cells
Tissue
Fibers
Composite materials

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Ricci, J., Gona, A. G., Alexander, H., & Parsons, J. R. (1985). COLLAGEN PRODUCTION BY RAT TENDON FIBROBLASTS CULTURED ON CARBON FILAMENT AND ON STANDARD CULTURE PLATES. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the Interna (Vol. 8, pp. 14). Soc for Biomaterials.

COLLAGEN PRODUCTION BY RAT TENDON FIBROBLASTS CULTURED ON CARBON FILAMENT AND ON STANDARD CULTURE PLATES. / Ricci, John; Gona, A. G.; Alexander, H.; Parsons, J. R.

Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the Interna. Vol. 8 Soc for Biomaterials, 1985. p. 14.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ricci, J, Gona, AG, Alexander, H & Parsons, JR 1985, COLLAGEN PRODUCTION BY RAT TENDON FIBROBLASTS CULTURED ON CARBON FILAMENT AND ON STANDARD CULTURE PLATES. in Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the Interna. vol. 8, Soc for Biomaterials, pp. 14.
Ricci J, Gona AG, Alexander H, Parsons JR. COLLAGEN PRODUCTION BY RAT TENDON FIBROBLASTS CULTURED ON CARBON FILAMENT AND ON STANDARD CULTURE PLATES. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the Interna. Vol. 8. Soc for Biomaterials. 1985. p. 14
Ricci, John ; Gona, A. G. ; Alexander, H. ; Parsons, J. R. / COLLAGEN PRODUCTION BY RAT TENDON FIBROBLASTS CULTURED ON CARBON FILAMENT AND ON STANDARD CULTURE PLATES. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the Interna. Vol. 8 Soc for Biomaterials, 1985. pp. 14
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