Circular Dichroism Imaging Microscopy: Application to Enantiomorphous Twinning in Biaxial Crystals of 1,8-Dihydroxyanthraquinone

Kacey Claborn, Eileen Puklin-Faucher, Miki Kurimoto, Werner Kaminsky, Bart Kahr

Research output: Contribution to journalArticle

Abstract

A microscope was constructed for imaging circular dichroism of heterogeneous anisotropic media. To avoid linear biases that are common with electronic circular polarization modulation, we chose a retrogressive solution: mechanical light modulation by rotating a linear polarizer with respect to a quarter wave plate continuously tuned by tilting to the operating wavelength. Our comparatively slow technique succeeds with near-perfect circular input and signal averaging using a CCD camera. We have applied the method to anomalously birefringent crystals of 1,8-dihydroxyanthraquinone that are shown to have intergrown mirror image domains, undetected by X-ray diffraction because the twinning complexity renders differences in anomalous dispersion, already small, unreliable. The origin of the anomalous birefringence and the assignment of the absolute configuration are discussed.

Original languageEnglish (US)
Pages (from-to)14825-14831
Number of pages7
JournalJournal of the American Chemical Society
Volume125
Issue number48
DOIs
StatePublished - Dec 3 2003

Fingerprint

Birefringence
Anisotropic media
Circular polarization
Light modulation
Twinning
Dichroism
CCD cameras
Circular Dichroism
X-Ray Diffraction
Microscopy
Microscopic examination
Mirrors
Microscopes
Modulation
Imaging techniques
Light
X ray diffraction
Wavelength
Crystals
danthron

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Circular Dichroism Imaging Microscopy : Application to Enantiomorphous Twinning in Biaxial Crystals of 1,8-Dihydroxyanthraquinone. / Claborn, Kacey; Puklin-Faucher, Eileen; Kurimoto, Miki; Kaminsky, Werner; Kahr, Bart.

In: Journal of the American Chemical Society, Vol. 125, No. 48, 03.12.2003, p. 14825-14831.

Research output: Contribution to journalArticle

Claborn, Kacey ; Puklin-Faucher, Eileen ; Kurimoto, Miki ; Kaminsky, Werner ; Kahr, Bart. / Circular Dichroism Imaging Microscopy : Application to Enantiomorphous Twinning in Biaxial Crystals of 1,8-Dihydroxyanthraquinone. In: Journal of the American Chemical Society. 2003 ; Vol. 125, No. 48. pp. 14825-14831.
@article{f3e5ca9dbb264bc68f6bcdb7d0029d23,
title = "Circular Dichroism Imaging Microscopy: Application to Enantiomorphous Twinning in Biaxial Crystals of 1,8-Dihydroxyanthraquinone",
abstract = "A microscope was constructed for imaging circular dichroism of heterogeneous anisotropic media. To avoid linear biases that are common with electronic circular polarization modulation, we chose a retrogressive solution: mechanical light modulation by rotating a linear polarizer with respect to a quarter wave plate continuously tuned by tilting to the operating wavelength. Our comparatively slow technique succeeds with near-perfect circular input and signal averaging using a CCD camera. We have applied the method to anomalously birefringent crystals of 1,8-dihydroxyanthraquinone that are shown to have intergrown mirror image domains, undetected by X-ray diffraction because the twinning complexity renders differences in anomalous dispersion, already small, unreliable. The origin of the anomalous birefringence and the assignment of the absolute configuration are discussed.",
author = "Kacey Claborn and Eileen Puklin-Faucher and Miki Kurimoto and Werner Kaminsky and Bart Kahr",
year = "2003",
month = "12",
day = "3",
doi = "10.1021/ja035644w",
language = "English (US)",
volume = "125",
pages = "14825--14831",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "American Chemical Society",
number = "48",

}

TY - JOUR

T1 - Circular Dichroism Imaging Microscopy

T2 - Application to Enantiomorphous Twinning in Biaxial Crystals of 1,8-Dihydroxyanthraquinone

AU - Claborn, Kacey

AU - Puklin-Faucher, Eileen

AU - Kurimoto, Miki

AU - Kaminsky, Werner

AU - Kahr, Bart

PY - 2003/12/3

Y1 - 2003/12/3

N2 - A microscope was constructed for imaging circular dichroism of heterogeneous anisotropic media. To avoid linear biases that are common with electronic circular polarization modulation, we chose a retrogressive solution: mechanical light modulation by rotating a linear polarizer with respect to a quarter wave plate continuously tuned by tilting to the operating wavelength. Our comparatively slow technique succeeds with near-perfect circular input and signal averaging using a CCD camera. We have applied the method to anomalously birefringent crystals of 1,8-dihydroxyanthraquinone that are shown to have intergrown mirror image domains, undetected by X-ray diffraction because the twinning complexity renders differences in anomalous dispersion, already small, unreliable. The origin of the anomalous birefringence and the assignment of the absolute configuration are discussed.

AB - A microscope was constructed for imaging circular dichroism of heterogeneous anisotropic media. To avoid linear biases that are common with electronic circular polarization modulation, we chose a retrogressive solution: mechanical light modulation by rotating a linear polarizer with respect to a quarter wave plate continuously tuned by tilting to the operating wavelength. Our comparatively slow technique succeeds with near-perfect circular input and signal averaging using a CCD camera. We have applied the method to anomalously birefringent crystals of 1,8-dihydroxyanthraquinone that are shown to have intergrown mirror image domains, undetected by X-ray diffraction because the twinning complexity renders differences in anomalous dispersion, already small, unreliable. The origin of the anomalous birefringence and the assignment of the absolute configuration are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0345724792&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0345724792&partnerID=8YFLogxK

U2 - 10.1021/ja035644w

DO - 10.1021/ja035644w

M3 - Article

VL - 125

SP - 14825

EP - 14831

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 48

ER -