Chondrocyte maturation on biphasic calcium phosphate scaffold: A preliminary study

C. C. Teixeira, R. Z. LeGeros, C. Karkia, Y. Nemelivsky

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A method of growing chondrocytes in a well characterized biphasic calcium phosphate (BCP) scaffold was studied. Chondrocytes were grown in culture continuously for 3 weeks, and fed every day with Dulbecco's modified Eagle medium (GIBCO) containing 10% Nu serum, 2mM L-glutamine, and 50 μg/ml ascorbic acid. Chondrocytes grown on BCP scaffold assumed an elongated morphology within an intricate net of collagenous protein, while cells grown on tissue culture plate surfaces maintained a polygon and flat morphology. The results show that a calcium phosphate scaffold can be used as a template for chondrocyte proliferation and maturation.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

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ASJC Scopus subject areas

  • Engineering(all)

Cite this

Teixeira, C. C., LeGeros, R. Z., Karkia, C., & Nemelivsky, Y. (2004). Chondrocyte maturation on biphasic calcium phosphate scaffold: A preliminary study. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).