Characterization and in vivo evaluation of laser sintered dental endosseous implants in dogs

Lukasz Witek, Charles Marin, Rodrigo Granato, Estevam A. Bonfante, Felipe Campos, Julio Bisinotto, Marcelo Suzuki, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Laser metal sintering has shown promising results, but no comparison with other commercially available surface has been performed. This study sought to evaluate the biomechanical and histological early bone response to laser sintered implants relative to alumina-blasted/acid-etched (AB/AE). Surface topography was characterized by scanning electron microscopy and optical interferometry. Surface chemistry was assessed by x-ray photoelectron spectroscopy. Beagle dogs (n = 18) received 4 Ti-6Al-4V implants (one per surface) in each radius, remaining for 1, 3, and 6 weeks (n = 6 dogs per evaluation time) in vivo. Bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated. Biomechanical evaluation comprised torque-to-interface failure. The laser sintered surface presented higher S a and S q than AB/AE. Chemistry assessment showed the alloy metallic components along with adsorbed carbon species. Significantly higher torque was observed at 1 (p < 0.02) and 6 week (p < 0.02) for the laser sintered, whereas at 3 week no significant differences were observed. Significantly higher BIC and BAFO was observed for the Laser Sintered (p < 0.04, and p < 0.03, respectively) only at 1 week, whereas no significant differences were observed at 3 and 6 weeks. The laser sintered implants presented biocompatible and osseoconductive properties and improved biomechanical response compared with the AB/AE surface only at 1 and 6 weeks in vivo.

Original languageEnglish (US)
Pages (from-to)1566-1573
Number of pages8
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume100 B
Issue number6
DOIs
StatePublished - Aug 2012

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Dental prostheses
Bone
Lasers
Aluminum Oxide
Alumina
Acids
Torque
Surface topography
Photoelectron spectroscopy
Surface chemistry
Interferometry
Sintering
Carbon
Metals
X rays
Scanning electron microscopy

Keywords

  • biomechanical
  • dental implant
  • histology
  • laser

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials

Cite this

Characterization and in vivo evaluation of laser sintered dental endosseous implants in dogs. / Witek, Lukasz; Marin, Charles; Granato, Rodrigo; Bonfante, Estevam A.; Campos, Felipe; Bisinotto, Julio; Suzuki, Marcelo; Coelho, Paulo.

In: Journal of Biomedical Materials Research - Part B Applied Biomaterials, Vol. 100 B, No. 6, 08.2012, p. 1566-1573.

Research output: Contribution to journalArticle

Witek, Lukasz ; Marin, Charles ; Granato, Rodrigo ; Bonfante, Estevam A. ; Campos, Felipe ; Bisinotto, Julio ; Suzuki, Marcelo ; Coelho, Paulo. / Characterization and in vivo evaluation of laser sintered dental endosseous implants in dogs. In: Journal of Biomedical Materials Research - Part B Applied Biomaterials. 2012 ; Vol. 100 B, No. 6. pp. 1566-1573.
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