Cercopithecine Y-chromosome data provide a test of competing morphological evolutionary hypotheses

Anthony J. Tosi, Todd Disotell, Juan Carlos Morales, Don J. Melnick

    Research output: Contribution to journalArticle

    Abstract

    We report here the results of the first molecular evolutionary analysis to include members of all 10 extant genera of cercopithecine monkeys. A total of 44 individuals were surveyed for ∼2.2 kb of the testis-specific protein, Y-chromosome (TSPY). The TSPY sequences were subjected to parsimony analyses in PAUP 4.0, followed by tree comparison tests designed to assess existing morphological hypotheses of cercopithecine evolution. The results of these tests show that the present Y-chromosome dataset unambiguously supports: (1) monophyly of Macaca, (2) polyphyly of the mangabeys (Cercocebus and Lophocebus), (3) paraphyly of Cercopithecus, and (4) inclusion of Allenopithecus and Miopithecus in the tribe Cercopithecini. A number of unexpected Y-chromosome relationships are also discussed, including a pattern suggesting resurrection of the genus Chlorocebus for the guenons currently identified as Erythrocebus patas, Cercopithecus aethiops, and Cercopithecus lhoesti. Relative rate tests reveal significant difference in the TSPY substitution rate across numerous lineages in the tribe Cercopithecini. Because the rate differences follow no obvious phylogenetic pattern, "local" molecular clocks were not employed and divergence dates were not estimated for this tribe. In contrast, similar analysis of the Papionini reveals rate heterogeneity between a single pair of taxonomic groups: Macaca vs. the "African papionins." Divergence dates were therefore calculated for the tribe by calibrating TSPY clocks specific to each of these two clades.

    Original languageEnglish (US)
    Pages (from-to)510-521
    Number of pages12
    JournalMolecular Phylogenetics and Evolution
    Volume27
    Issue number3
    DOIs
    StatePublished - Jun 1 2003

    Fingerprint

    Y Chromosome
    Y chromosome
    chromosome
    Cercocebus
    Testis
    testes
    Cercopithecus
    protein
    testing
    Macaca
    Proteins
    Erythrocebus patas
    proteins
    divergence
    Erythrocebus
    chromosome substitution
    polyphyly
    Cercopithecus aethiops
    paraphyly
    monophyly

    Keywords

    • Cercopithecinae
    • Cercopithecini
    • Molecular systematics
    • Papionini
    • TSPY

    ASJC Scopus subject areas

    • Ecology, Evolution, Behavior and Systematics
    • Molecular Biology
    • Genetics

    Cite this

    Cercopithecine Y-chromosome data provide a test of competing morphological evolutionary hypotheses. / Tosi, Anthony J.; Disotell, Todd; Morales, Juan Carlos; Melnick, Don J.

    In: Molecular Phylogenetics and Evolution, Vol. 27, No. 3, 01.06.2003, p. 510-521.

    Research output: Contribution to journalArticle

    Tosi, Anthony J. ; Disotell, Todd ; Morales, Juan Carlos ; Melnick, Don J. / Cercopithecine Y-chromosome data provide a test of competing morphological evolutionary hypotheses. In: Molecular Phylogenetics and Evolution. 2003 ; Vol. 27, No. 3. pp. 510-521.
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