Cellular analysis of long-term habituation of the gill-withdrawal reflex of Aplysia californica

V. F. Castellucci, Thomas Carew, E. R. Kandel

Research output: Contribution to journalArticle

Abstract

Long-term habituation training in Aplysia californica produces a profound depression in the efficacy of synaptic transmission between mechanoreceptor neurons and gill motor neurons. This depression persists for more than 3 weeks. Thus a critical synaptic site for plasticity underlying long-term habituation is the same as that for short-term habituation. For this simple form of learning, short- and long-term memory share a common locus and aspects of a common mechanism: synaptic depression.

Original languageEnglish (US)
Pages (from-to)1306-1308
Number of pages3
JournalScience
Volume202
Issue number4374
StatePublished - 1978

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Aplysia
Reflex
Depression
Mechanoreceptors
Neuronal Plasticity
Long-Term Memory
Motor Neurons
Synaptic Transmission
Learning
Neurons

ASJC Scopus subject areas

  • General

Cite this

Cellular analysis of long-term habituation of the gill-withdrawal reflex of Aplysia californica. / Castellucci, V. F.; Carew, Thomas; Kandel, E. R.

In: Science, Vol. 202, No. 4374, 1978, p. 1306-1308.

Research output: Contribution to journalArticle

Castellucci, VF, Carew, T & Kandel, ER 1978, 'Cellular analysis of long-term habituation of the gill-withdrawal reflex of Aplysia californica', Science, vol. 202, no. 4374, pp. 1306-1308.
Castellucci, V. F. ; Carew, Thomas ; Kandel, E. R. / Cellular analysis of long-term habituation of the gill-withdrawal reflex of Aplysia californica. In: Science. 1978 ; Vol. 202, No. 4374. pp. 1306-1308.
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