Catalysis of 6π electrocyclizations

Lee M. Bishop, Jennifer E. Barbarow, Robert G. Bergman, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

(Chemical Equation Presented) Filling the gap: Lewis acid catalysis ofa 6π electrocyclization has been achieved for the first time (see scheme). DFT calculations were performed on the coordination ofa Lewis acid to a Lewis basic group in the 2-position ofa triene, and experimentally, the rates ofthe electrocyclization increase in the presence of Me2AlCl.

Original languageEnglish (US)
Pages (from-to)8100-8103
Number of pages4
JournalAngewandte Chemie - International Edition
Volume47
Issue number42
DOIs
StatePublished - Oct 6 2008

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Keywords

  • Cyclization
  • Density functional calculations
  • Homogeneous catalysis
  • Pericyclic reaction
  • Transition states

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Bishop, L. M., Barbarow, J. E., Bergman, R. G., & Trauner, D. (2008). Catalysis of 6π electrocyclizations. Angewandte Chemie - International Edition, 47(42), 8100-8103. https://doi.org/10.1002/anie.200803336