Cannabinoids and viral infections

Research output: Contribution to journalArticle

Abstract

Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antiviral/pro-resolution responses include the activation of NOS-1, inhibition of Ca2+ activity by cannabinoids, increased viral replication and disease. This review examines the effect(s) of cannabinoids and their antagonists in viral infections.

Original languageEnglish (US)
Pages (from-to)1873-1886
Number of pages14
JournalPharmaceuticals
Volume3
Issue number6
DOIs
StatePublished - 2010

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Cannabinoids
Virus Diseases
Cannabinoid Receptor Antagonists
Antiviral Agents
Anti-Inflammatory Agents
Neurons
Infection

Keywords

  • Immunomodulation
  • Inflammation
  • Pathogens
  • Virus infection

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmaceutical Science

Cite this

Cannabinoids and viral infections. / Reiss, Carol.

In: Pharmaceuticals, Vol. 3, No. 6, 2010, p. 1873-1886.

Research output: Contribution to journalArticle

Reiss, Carol. / Cannabinoids and viral infections. In: Pharmaceuticals. 2010 ; Vol. 3, No. 6. pp. 1873-1886.
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