Bone regeneration around implants placed in fresh extraction sockets covered with a dual-layer PTFE/collagen membrane: An experimental study in dogs

Nick Tovar, Ryo Jimbo, Charles Marin, Lukasz Witek, Marcelo Suzuki, Estevam A Bonfante, Paulo G Coelho

Research output: Contribution to journalArticle


This study investigated whether the use of a dual-layer polytetrafluoroethylene (PTFE)/porcine-derived bioresorbable pericardium membrane enhances the osseointegration around implants compared to a single-layer porcine-derived bioresorbable pericardium membrane and a no-membrane control group. Endosseous implants were placed in the fresh extraction sockets of beagles. At 6 weeks, bone loss and apical soft tissue migration occurred in the control group, whereas bone successfully formed to the neck of the implant for the single-layer porcine-derived bioresorbable pericardium membrane group. The dual-layer PTFE/ porcine-derived bioresorbable pericardium membrane showed bone growth coronal to the neck of the implant. Bone-to-implant contact and buccal bone loss were respectively higher and lower relative to the single-layer but not statistically different.

Original languageEnglish (US)
Article numberdoi: 10.11607/prd.1723, PMID: 25411741
Pages (from-to)849-55
Number of pages7
JournalThe International journal of periodontics & restorative dentistry
Issue number6
StatePublished - Nov 21 2014


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