Blunt-ended DNA stacking interactions in a 3-helix motif

Risheng Wang, Akinori Kuzuya, Wenyan Liu, Nadrian Seeman

Research output: Contribution to journalArticle

Abstract

We demonstrate that intermolecular stacking is capable of forming one-dimensional arrays of a blunt-ended 3-helix DNA motif. The array can be visualized in the atomic force microscopy through conjugated streptavidin nanoparticles. We estimate the strength of the triple stacking interaction to be -8.6 kcal mol-1.

Original languageEnglish (US)
Pages (from-to)4905-4907
Number of pages3
JournalChemical Communications
Volume46
Issue number27
DOIs
StatePublished - 2010

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Nucleotide Motifs
Streptavidin
Atomic Force Microscopy
Nanoparticles
Atomic force microscopy
DNA

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys
  • Medicine(all)

Cite this

Blunt-ended DNA stacking interactions in a 3-helix motif. / Wang, Risheng; Kuzuya, Akinori; Liu, Wenyan; Seeman, Nadrian.

In: Chemical Communications, Vol. 46, No. 27, 2010, p. 4905-4907.

Research output: Contribution to journalArticle

Wang, Risheng ; Kuzuya, Akinori ; Liu, Wenyan ; Seeman, Nadrian. / Blunt-ended DNA stacking interactions in a 3-helix motif. In: Chemical Communications. 2010 ; Vol. 46, No. 27. pp. 4905-4907.
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