Bionanocomposites: Differential effects of cellulose nanocrystals on protein diblock copolymers

Jennifer S. Haghpanah, Raymond Tu, Sandra Da Silva, Deng Yan, Silvana Mueller, Christoph Weder, E. Johan Foster, Iulia Sacui, Jeffery W. Gilman, Jin Montclare

Research output: Contribution to journalArticle

Abstract

We investigate the effects of mixing a colloidal suspension of tunicate-derived cellulose nanocrystals (t-CNCs) with aqueous colloidal suspensions of two protein diblock copolymers, EC and CE, which bear two different self-assembling domains (SADs) derived from elastin (E) and the coiled-coil region of cartilage oligomeric matrix protein (C). The resulting aqueous mixtures reveal improved mechanical integrity for the CE+t-CNC mixture, which exhibits an elastic gel network. This is in contrast to EC+t-CNC, which does not form a gel, indicating that block orientation influences the ability to interact with t-CNCs. Surface analysis and interfacial characterization indicate that the differential mechanical properties of the two samples are due to the prevalent display of the E domain by CE, which interacts more with t-CNCs leading to a stronger network with t-CNCs. On the other hand, EC, which is predominantly C-rich on its surface, does not interact as much with t-CNCs. This suggests that the surface characteristics of the protein polymers, due to folding and self-assembly, are important factors for the interactions with t-CNCs, and a significant influence on the overall mechanical properties. These results have interesting implications for the understanding of cellulose hydrophobic interactions, natural biomaterials and the development of artificially assembled bionanocomposites.

Original languageEnglish (US)
Pages (from-to)4360-4367
Number of pages8
JournalBiomacromolecules
Volume14
Issue number12
DOIs
StatePublished - Dec 9 2013

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Cellulose
Nanocrystals
Block copolymers
Proteins
Suspensions
Gels
Cartilage Oligomeric Matrix Protein
Elastin
Mechanical properties
Surface analysis
Cartilage
Beam plasma interactions
Biocompatible Materials
Biomaterials
Crystal orientation
Self assembly
Polymers
Membrane Proteins
Display devices

ASJC Scopus subject areas

  • Bioengineering
  • Materials Chemistry
  • Polymers and Plastics
  • Biomaterials

Cite this

Bionanocomposites : Differential effects of cellulose nanocrystals on protein diblock copolymers. / Haghpanah, Jennifer S.; Tu, Raymond; Da Silva, Sandra; Yan, Deng; Mueller, Silvana; Weder, Christoph; Foster, E. Johan; Sacui, Iulia; Gilman, Jeffery W.; Montclare, Jin.

In: Biomacromolecules, Vol. 14, No. 12, 09.12.2013, p. 4360-4367.

Research output: Contribution to journalArticle

Haghpanah, JS, Tu, R, Da Silva, S, Yan, D, Mueller, S, Weder, C, Foster, EJ, Sacui, I, Gilman, JW & Montclare, J 2013, 'Bionanocomposites: Differential effects of cellulose nanocrystals on protein diblock copolymers', Biomacromolecules, vol. 14, no. 12, pp. 4360-4367. https://doi.org/10.1021/bm401304w
Haghpanah JS, Tu R, Da Silva S, Yan D, Mueller S, Weder C et al. Bionanocomposites: Differential effects of cellulose nanocrystals on protein diblock copolymers. Biomacromolecules. 2013 Dec 9;14(12):4360-4367. https://doi.org/10.1021/bm401304w
Haghpanah, Jennifer S. ; Tu, Raymond ; Da Silva, Sandra ; Yan, Deng ; Mueller, Silvana ; Weder, Christoph ; Foster, E. Johan ; Sacui, Iulia ; Gilman, Jeffery W. ; Montclare, Jin. / Bionanocomposites : Differential effects of cellulose nanocrystals on protein diblock copolymers. In: Biomacromolecules. 2013 ; Vol. 14, No. 12. pp. 4360-4367.
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