Biomechanical Evaluation of Endosseous Implants at Early Implantation Times: A Study in Dogs

Paulo Coelho, Rodrigo Granato, Charles Marin, Estevam A. Bonfante, Jose N O Freire, Malvin N. Janal, Jose N. Gil, Marcelo Suzuki

Research output: Contribution to journalArticle

Abstract

Purpose: This study tested the null hypothesis that differences in surgical instrumentation, macrogeometry, and surface treatment imposed by different implant systems do not affect early biomechanical fixation in a canine mandible model. Materials and Methods: The lower premolars of 6 beagle dogs were extracted and the ridges allowed to heal for 8 weeks. Thirty-six (n = 12 each group) implants were bilaterally placed, remaining for 1 and 3 weeks in vivo. The implant groups were as follows: group 1, Ti-6Al-4V with a dual acid-etched surface with nanometer scale discrete crystalline deposition (Nanotite; Certain Biomet-3i, West Palm Springs, FL); group 2, Ti-6Al-4V with a titanium oxide-blasted fluoride-modified surface chemistry (Osseospeed 4.0 S; Astra Tech, Mölndal, Sweden); group 3: Ti-6Al-4V with a bioceramic microblasted surface (Ossean; Intra-Lock International, Boca Raton, FL). Following euthanasia, implants were torqued to interface failure and histologically evaluated. General linear modeling (ANOVA) at 95% level of significance was performed. Results: Histology showed that interfacial bone remodeling and initial woven bone formation were observed around all implant groups at 1 and 3 weeks. Torque values were significantly affected by time in vivo, implant group, and their interaction (P = .016, P < .001, and P = .001, respectively). Regarding torque values, group 3, group 2, and group 1 ranked highest, intermediate, and lowest, respectively. Conclusion: Early biomechanical fixation at 1 and 3 weeks was affected by surgical instrumentation, macrogeometry, and surface treatment present for one of the implant systems tested. The null hypothesis was rejected.

Original languageEnglish (US)
Pages (from-to)1667-1675
Number of pages9
JournalJournal of Oral and Maxillofacial Surgery
Volume68
Issue number7
DOIs
StatePublished - Jul 2010

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Torque
Dogs
Euthanasia
Bone Remodeling
Cimetidine
Bicuspid
Fluorides
Mandible
Sweden
Osteogenesis
Canidae
Histology
Analysis of Variance
Acids
Therapeutics
titanium dioxide

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology
  • Surgery

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Biomechanical Evaluation of Endosseous Implants at Early Implantation Times : A Study in Dogs. / Coelho, Paulo; Granato, Rodrigo; Marin, Charles; Bonfante, Estevam A.; Freire, Jose N O; Janal, Malvin N.; Gil, Jose N.; Suzuki, Marcelo.

In: Journal of Oral and Maxillofacial Surgery, Vol. 68, No. 7, 07.2010, p. 1667-1675.

Research output: Contribution to journalArticle

Coelho, P, Granato, R, Marin, C, Bonfante, EA, Freire, JNO, Janal, MN, Gil, JN & Suzuki, M 2010, 'Biomechanical Evaluation of Endosseous Implants at Early Implantation Times: A Study in Dogs', Journal of Oral and Maxillofacial Surgery, vol. 68, no. 7, pp. 1667-1675. https://doi.org/10.1016/j.joms.2010.02.050
Coelho, Paulo ; Granato, Rodrigo ; Marin, Charles ; Bonfante, Estevam A. ; Freire, Jose N O ; Janal, Malvin N. ; Gil, Jose N. ; Suzuki, Marcelo. / Biomechanical Evaluation of Endosseous Implants at Early Implantation Times : A Study in Dogs. In: Journal of Oral and Maxillofacial Surgery. 2010 ; Vol. 68, No. 7. pp. 1667-1675.
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abstract = "Purpose: This study tested the null hypothesis that differences in surgical instrumentation, macrogeometry, and surface treatment imposed by different implant systems do not affect early biomechanical fixation in a canine mandible model. Materials and Methods: The lower premolars of 6 beagle dogs were extracted and the ridges allowed to heal for 8 weeks. Thirty-six (n = 12 each group) implants were bilaterally placed, remaining for 1 and 3 weeks in vivo. The implant groups were as follows: group 1, Ti-6Al-4V with a dual acid-etched surface with nanometer scale discrete crystalline deposition (Nanotite; Certain Biomet-3i, West Palm Springs, FL); group 2, Ti-6Al-4V with a titanium oxide-blasted fluoride-modified surface chemistry (Osseospeed 4.0 S; Astra Tech, M{\"o}lndal, Sweden); group 3: Ti-6Al-4V with a bioceramic microblasted surface (Ossean; Intra-Lock International, Boca Raton, FL). Following euthanasia, implants were torqued to interface failure and histologically evaluated. General linear modeling (ANOVA) at 95{\%} level of significance was performed. Results: Histology showed that interfacial bone remodeling and initial woven bone formation were observed around all implant groups at 1 and 3 weeks. Torque values were significantly affected by time in vivo, implant group, and their interaction (P = .016, P < .001, and P = .001, respectively). Regarding torque values, group 3, group 2, and group 1 ranked highest, intermediate, and lowest, respectively. Conclusion: Early biomechanical fixation at 1 and 3 weeks was affected by surgical instrumentation, macrogeometry, and surface treatment present for one of the implant systems tested. The null hypothesis was rejected.",
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T2 - A Study in Dogs

AU - Coelho, Paulo

AU - Granato, Rodrigo

AU - Marin, Charles

AU - Bonfante, Estevam A.

AU - Freire, Jose N O

AU - Janal, Malvin N.

AU - Gil, Jose N.

AU - Suzuki, Marcelo

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N2 - Purpose: This study tested the null hypothesis that differences in surgical instrumentation, macrogeometry, and surface treatment imposed by different implant systems do not affect early biomechanical fixation in a canine mandible model. Materials and Methods: The lower premolars of 6 beagle dogs were extracted and the ridges allowed to heal for 8 weeks. Thirty-six (n = 12 each group) implants were bilaterally placed, remaining for 1 and 3 weeks in vivo. The implant groups were as follows: group 1, Ti-6Al-4V with a dual acid-etched surface with nanometer scale discrete crystalline deposition (Nanotite; Certain Biomet-3i, West Palm Springs, FL); group 2, Ti-6Al-4V with a titanium oxide-blasted fluoride-modified surface chemistry (Osseospeed 4.0 S; Astra Tech, Mölndal, Sweden); group 3: Ti-6Al-4V with a bioceramic microblasted surface (Ossean; Intra-Lock International, Boca Raton, FL). Following euthanasia, implants were torqued to interface failure and histologically evaluated. General linear modeling (ANOVA) at 95% level of significance was performed. Results: Histology showed that interfacial bone remodeling and initial woven bone formation were observed around all implant groups at 1 and 3 weeks. Torque values were significantly affected by time in vivo, implant group, and their interaction (P = .016, P < .001, and P = .001, respectively). Regarding torque values, group 3, group 2, and group 1 ranked highest, intermediate, and lowest, respectively. Conclusion: Early biomechanical fixation at 1 and 3 weeks was affected by surgical instrumentation, macrogeometry, and surface treatment present for one of the implant systems tested. The null hypothesis was rejected.

AB - Purpose: This study tested the null hypothesis that differences in surgical instrumentation, macrogeometry, and surface treatment imposed by different implant systems do not affect early biomechanical fixation in a canine mandible model. Materials and Methods: The lower premolars of 6 beagle dogs were extracted and the ridges allowed to heal for 8 weeks. Thirty-six (n = 12 each group) implants were bilaterally placed, remaining for 1 and 3 weeks in vivo. The implant groups were as follows: group 1, Ti-6Al-4V with a dual acid-etched surface with nanometer scale discrete crystalline deposition (Nanotite; Certain Biomet-3i, West Palm Springs, FL); group 2, Ti-6Al-4V with a titanium oxide-blasted fluoride-modified surface chemistry (Osseospeed 4.0 S; Astra Tech, Mölndal, Sweden); group 3: Ti-6Al-4V with a bioceramic microblasted surface (Ossean; Intra-Lock International, Boca Raton, FL). Following euthanasia, implants were torqued to interface failure and histologically evaluated. General linear modeling (ANOVA) at 95% level of significance was performed. Results: Histology showed that interfacial bone remodeling and initial woven bone formation were observed around all implant groups at 1 and 3 weeks. Torque values were significantly affected by time in vivo, implant group, and their interaction (P = .016, P < .001, and P = .001, respectively). Regarding torque values, group 3, group 2, and group 1 ranked highest, intermediate, and lowest, respectively. Conclusion: Early biomechanical fixation at 1 and 3 weeks was affected by surgical instrumentation, macrogeometry, and surface treatment present for one of the implant systems tested. The null hypothesis was rejected.

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