Biomechanical and histological analysis of an HA coated, arc deposited CPTi canine hip prosthesis

Matthew T. Walenciak, Mark C. Zimmerman, Robert D. Harten, John Ricci, David T. Stamer

Research output: Contribution to journalArticle

Abstract

The interfacial shear strength and bone tissue response was investigated for an arc deposited (AD) commercially pure titanium implant surface, with (AD/HA) and without (AD) plasma-sprayed hydroxyapatite (HA) coating. Ten purpose bred coonhounds received bilateral femoral stem implantation (AD and AD/HA) in the proximal femurs (hemiarthroplasty). The femoral prosthesis consisted of a modular CoCr alloy head, modular Ti-6Al-4V neck, and a 10-mm diameter cylindrical Ti-6Al-4V femoral stem. The AD surface had 30-35% greater surface roughness than the AD/HA surface. The HA coating had a purity greater than 90% and a crystallinity greater than 65%. After 6, 12, and 24 weeks, the implants were retrieved and analyzed with mechanical testing, qualitative and quantitative histology, and electron microscopy. The AD/HA implants had equivalent interfacial shear strengths to the AD implants at all time periods. The AD/HA implants had significantly greater linear bone contact than the AD implants. The 6-week implants had significantly thicker cortical bone than the 12- and 24-week implants. The HA coating was very stable in vivo, evidenced by no thickness reduction at any time period. Qualitatively, the AD/HA implants primarily had bone contacting the implant surface with little fibrous tissue present, and the AD implants had bone and fibrous tissue contacting the implant surface. The electron microscopy analysis showed that the mechanically tested implants exhibited a mixed failure mode at the bone, HA coating, and titanium interfaces.

Original languageEnglish (US)
Pages (from-to)465-474
Number of pages10
JournalJournal of Biomedical Materials Research
Volume31
Issue number4
DOIs
StatePublished - Aug 1996

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Hip prostheses
Durapatite
Hydroxyapatite
Bone
Coatings
Tissue
Titanium
Shear strength
Electron microscopy
Histology
Mechanical testing
Failure modes
Surface roughness

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials

Cite this

Biomechanical and histological analysis of an HA coated, arc deposited CPTi canine hip prosthesis. / Walenciak, Matthew T.; Zimmerman, Mark C.; Harten, Robert D.; Ricci, John; Stamer, David T.

In: Journal of Biomedical Materials Research, Vol. 31, No. 4, 08.1996, p. 465-474.

Research output: Contribution to journalArticle

Walenciak, Matthew T. ; Zimmerman, Mark C. ; Harten, Robert D. ; Ricci, John ; Stamer, David T. / Biomechanical and histological analysis of an HA coated, arc deposited CPTi canine hip prosthesis. In: Journal of Biomedical Materials Research. 1996 ; Vol. 31, No. 4. pp. 465-474.
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