Bhc-diol as a photolabile protecting group for aldehydes and ketones

Min Lu, Olesya D. Fedoryak, Brent R. Moister, Timothy Dore

Research output: Contribution to journalArticle

Abstract

(Matrix presented) 6-Bromo-4-(1,2-dihydroxyethyl)-7-hydroxycoumarin (Bhc-diol) can be used under simulated physiological conditions as a photoremovable protecting group for aldehydes and ketones. The single- and two-photon-induced release of benzaldehyde, piperonal, acetophenone, and cyclohexanone is demonstrated.

Original languageEnglish (US)
Pages (from-to)2119-2122
Number of pages4
JournalOrganic Letters
Volume5
Issue number12
DOIs
StatePublished - Jun 12 2003

Fingerprint

7-hydroxycoumarin
Ketones
aldehydes
Photons
Aldehydes
ketones
photons
matrices
benzaldehyde
cyclohexanone
acetophenone
piperonal

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Bhc-diol as a photolabile protecting group for aldehydes and ketones. / Lu, Min; Fedoryak, Olesya D.; Moister, Brent R.; Dore, Timothy.

In: Organic Letters, Vol. 5, No. 12, 12.06.2003, p. 2119-2122.

Research output: Contribution to journalArticle

Lu, Min ; Fedoryak, Olesya D. ; Moister, Brent R. ; Dore, Timothy. / Bhc-diol as a photolabile protecting group for aldehydes and ketones. In: Organic Letters. 2003 ; Vol. 5, No. 12. pp. 2119-2122.
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