Associative learning in Aplysia: Evidence for conditioned fear in an invertebrate

Edgar T. Walters, Thomas Carew, Eric R. Kandel

Research output: Contribution to journalArticle

Abstract

Aversive classical conditioning of Aplysia californica, a gastropod mollusk suited for neurobiological study, produces a learned reaction to the chemosensory conditioned stimulus that is expressed as a marked facilitation of four defensive responses: two graded reflexes (head and siphon withdrawal), an all-or-none fixed act (inking), and a complex fixed action pattern (escape locomotion). In addition, the conditioned stimulus produces a concomitant depression of at least one appetitive response, feeding. These extensive and selective actions of the conditioned stimulus in Aplysia resemble the actions of conditioned fear stimuli in higher mammals and suggest that the functional equivalent of fear occurs in invertebrates and thus may be an adaptive mechanism that is widespread in the animal kingdom.

Original languageEnglish (US)
Pages (from-to)504-506
Number of pages3
JournalScience
Volume211
Issue number4481
StatePublished - 1981

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Aplysia
Invertebrates
Fear
Learning
Instinct
Gastropoda
Classical Conditioning
Mollusca
Locomotion
Reflex
Mammals
Head

ASJC Scopus subject areas

  • General

Cite this

Associative learning in Aplysia : Evidence for conditioned fear in an invertebrate. / Walters, Edgar T.; Carew, Thomas; Kandel, Eric R.

In: Science, Vol. 211, No. 4481, 1981, p. 504-506.

Research output: Contribution to journalArticle

Walters, ET, Carew, T & Kandel, ER 1981, 'Associative learning in Aplysia: Evidence for conditioned fear in an invertebrate', Science, vol. 211, no. 4481, pp. 504-506.
Walters, Edgar T. ; Carew, Thomas ; Kandel, Eric R. / Associative learning in Aplysia : Evidence for conditioned fear in an invertebrate. In: Science. 1981 ; Vol. 211, No. 4481. pp. 504-506.
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