Association between Oral Health and Cognitive Status

A Systematic Review

Bei Wu, Gerda G. Fillenbaum, Brenda L. Plassman, Liang Guo

Research output: Contribution to journalReview article

Abstract

Objectives To systematically review longitudinal studies examining the association between oral health and cognitive decline. Design Studies published between January 1993 and March 2013 were identified by search of English language publications in PubMed/Medline using relevant Medical Subject Heading terms and title and abstract keywords and from CINAHL using relevant subject headings. After applying eligibility criteria and adding four studies identified from article references, 56 of the 1,412 articles identified remained; 40 were cross-sectional, and 16 were longitudinal; 11 of the latter examined the effect of oral health on change in cognitive health or dementia incidence, five examined the reverse. Setting Sources of information included administrative data, subject evaluations in parent studies, medical and dental records, self-reports, and in-person evaluations. Participants Older adults. Measurements Most studies used subjects whose oral or cognitive status was known, using standard approaches to impute for missing information. The oral health information most frequently studied included number of teeth, periodontal and caries problems, and denture use. Cognition was most frequently evaluated using the Mini-Mental State Examination or according to a diagnosis of dementia. Results Some studies found that oral health measures such as number of teeth and periodontal disease were associated with risk of cognitive decline or incident dementia, whereas others did not find an association. Similarly, cognitive decline was not consistently associated with greater loss of teeth or number of decayed teeth. It is likely that methodological limitations play a major role in explaining the inconsistent findings. Conclusion It is unclear how or whether oral health and cognitive status are related. Additional research is needed in which there is greater agreement on how oral health and cognitive states are assessed to better examine the linkages between these two health outcomes.

Original languageEnglish (US)
Pages (from-to)739-751
Number of pages13
JournalJournal of the American Geriatrics Society
Volume64
Issue number4
DOIs
StatePublished - Apr 1 2016

Fingerprint

Oral Health
Health Status
Dementia
Tooth
Tooth Diseases
Dental Records
Medical Subject Headings
Tooth Loss
Dentures
Health
Periodontal Diseases
PubMed
Self Report
Cognition
Medical Records
Longitudinal Studies
Publications
Language
Incidence
Research

Keywords

  • cognitive decline
  • dementia
  • oral health

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Association between Oral Health and Cognitive Status : A Systematic Review. / Wu, Bei; Fillenbaum, Gerda G.; Plassman, Brenda L.; Guo, Liang.

In: Journal of the American Geriatrics Society, Vol. 64, No. 4, 01.04.2016, p. 739-751.

Research output: Contribution to journalReview article

Wu, Bei ; Fillenbaum, Gerda G. ; Plassman, Brenda L. ; Guo, Liang. / Association between Oral Health and Cognitive Status : A Systematic Review. In: Journal of the American Geriatrics Society. 2016 ; Vol. 64, No. 4. pp. 739-751.
@article{fa1c849ca9e6452b860d878b900cb44c,
title = "Association between Oral Health and Cognitive Status: A Systematic Review",
abstract = "Objectives To systematically review longitudinal studies examining the association between oral health and cognitive decline. Design Studies published between January 1993 and March 2013 were identified by search of English language publications in PubMed/Medline using relevant Medical Subject Heading terms and title and abstract keywords and from CINAHL using relevant subject headings. After applying eligibility criteria and adding four studies identified from article references, 56 of the 1,412 articles identified remained; 40 were cross-sectional, and 16 were longitudinal; 11 of the latter examined the effect of oral health on change in cognitive health or dementia incidence, five examined the reverse. Setting Sources of information included administrative data, subject evaluations in parent studies, medical and dental records, self-reports, and in-person evaluations. Participants Older adults. Measurements Most studies used subjects whose oral or cognitive status was known, using standard approaches to impute for missing information. The oral health information most frequently studied included number of teeth, periodontal and caries problems, and denture use. Cognition was most frequently evaluated using the Mini-Mental State Examination or according to a diagnosis of dementia. Results Some studies found that oral health measures such as number of teeth and periodontal disease were associated with risk of cognitive decline or incident dementia, whereas others did not find an association. Similarly, cognitive decline was not consistently associated with greater loss of teeth or number of decayed teeth. It is likely that methodological limitations play a major role in explaining the inconsistent findings. Conclusion It is unclear how or whether oral health and cognitive status are related. Additional research is needed in which there is greater agreement on how oral health and cognitive states are assessed to better examine the linkages between these two health outcomes.",
keywords = "cognitive decline, dementia, oral health",
author = "Bei Wu and Fillenbaum, {Gerda G.} and Plassman, {Brenda L.} and Liang Guo",
year = "2016",
month = "4",
day = "1",
doi = "10.1111/jgs.14036",
language = "English (US)",
volume = "64",
pages = "739--751",
journal = "Journal of the American Geriatrics Society",
issn = "0002-8614",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Association between Oral Health and Cognitive Status

T2 - A Systematic Review

AU - Wu, Bei

AU - Fillenbaum, Gerda G.

AU - Plassman, Brenda L.

AU - Guo, Liang

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Objectives To systematically review longitudinal studies examining the association between oral health and cognitive decline. Design Studies published between January 1993 and March 2013 were identified by search of English language publications in PubMed/Medline using relevant Medical Subject Heading terms and title and abstract keywords and from CINAHL using relevant subject headings. After applying eligibility criteria and adding four studies identified from article references, 56 of the 1,412 articles identified remained; 40 were cross-sectional, and 16 were longitudinal; 11 of the latter examined the effect of oral health on change in cognitive health or dementia incidence, five examined the reverse. Setting Sources of information included administrative data, subject evaluations in parent studies, medical and dental records, self-reports, and in-person evaluations. Participants Older adults. Measurements Most studies used subjects whose oral or cognitive status was known, using standard approaches to impute for missing information. The oral health information most frequently studied included number of teeth, periodontal and caries problems, and denture use. Cognition was most frequently evaluated using the Mini-Mental State Examination or according to a diagnosis of dementia. Results Some studies found that oral health measures such as number of teeth and periodontal disease were associated with risk of cognitive decline or incident dementia, whereas others did not find an association. Similarly, cognitive decline was not consistently associated with greater loss of teeth or number of decayed teeth. It is likely that methodological limitations play a major role in explaining the inconsistent findings. Conclusion It is unclear how or whether oral health and cognitive status are related. Additional research is needed in which there is greater agreement on how oral health and cognitive states are assessed to better examine the linkages between these two health outcomes.

AB - Objectives To systematically review longitudinal studies examining the association between oral health and cognitive decline. Design Studies published between January 1993 and March 2013 were identified by search of English language publications in PubMed/Medline using relevant Medical Subject Heading terms and title and abstract keywords and from CINAHL using relevant subject headings. After applying eligibility criteria and adding four studies identified from article references, 56 of the 1,412 articles identified remained; 40 were cross-sectional, and 16 were longitudinal; 11 of the latter examined the effect of oral health on change in cognitive health or dementia incidence, five examined the reverse. Setting Sources of information included administrative data, subject evaluations in parent studies, medical and dental records, self-reports, and in-person evaluations. Participants Older adults. Measurements Most studies used subjects whose oral or cognitive status was known, using standard approaches to impute for missing information. The oral health information most frequently studied included number of teeth, periodontal and caries problems, and denture use. Cognition was most frequently evaluated using the Mini-Mental State Examination or according to a diagnosis of dementia. Results Some studies found that oral health measures such as number of teeth and periodontal disease were associated with risk of cognitive decline or incident dementia, whereas others did not find an association. Similarly, cognitive decline was not consistently associated with greater loss of teeth or number of decayed teeth. It is likely that methodological limitations play a major role in explaining the inconsistent findings. Conclusion It is unclear how or whether oral health and cognitive status are related. Additional research is needed in which there is greater agreement on how oral health and cognitive states are assessed to better examine the linkages between these two health outcomes.

KW - cognitive decline

KW - dementia

KW - oral health

UR - http://www.scopus.com/inward/record.url?scp=84963491082&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84963491082&partnerID=8YFLogxK

U2 - 10.1111/jgs.14036

DO - 10.1111/jgs.14036

M3 - Review article

VL - 64

SP - 739

EP - 751

JO - Journal of the American Geriatrics Society

JF - Journal of the American Geriatrics Society

SN - 0002-8614

IS - 4

ER -