Aryl-linked imidazolidin-2-ones as non-peptidic β-strand mimetics

Charlotte L. Sutherell, Sam Thompson, Richard T.W. Scott, Andrew D. Hamilton

Research output: Contribution to journalArticle

Abstract

We describe the design and synthesis of a non-peptidic β-strand mimetic composed of alternating aryl and imidazolidin-2-one rings that can be adapted to display diverse side-chains. Solid- and solution-phase data together with calculations suggest that the desired conformation for side-chain mimicry is readily accessible and well-populated.

Original languageEnglish (US)
Pages (from-to)9834-9836
Number of pages3
JournalChemical Communications
Volume48
Issue number79
DOIs
StatePublished - Sep 10 2012

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ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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