Applications of confocal microscopy to the study of myelin development and neuron structure

S. M. Staugaitis, T. Rowan, Dan Sanes, D. R. Colman, P. R. Smith

Research output: Contribution to journalArticle

Abstract

Confocal laser scanning microscopy has been used to study the localization of myelin basic proteins expressed in nonglial cells, and to probe the three-dimensional structure of central auditory neurons in the lateral superior olive. The paper focuses on the techniques used to obtain the results. The key roles of confocal microscopy and computer image processing of the images obtained are emphasized as they relate to the discovery of essential structural information about these specimens.

Original languageEnglish (US)
Pages (from-to)31-37
Number of pages7
JournalJournal of Electron Microscopy Technique
Volume18
Issue number1
StatePublished - 1991

Fingerprint

myelin
Confocal microscopy
Myelin Sheath
neurons
Confocal Microscopy
Neurons
Microscopic examination
Image processing
microscopy
Proteins
Scanning
Myelin Basic Protein
Lasers
image processing
proteins
scanning
probes
cells
lasers
Superior Olivary Complex

Keywords

  • Computer image processing
  • LSO neurons
  • Myelin basic protein

ASJC Scopus subject areas

  • Anatomy

Cite this

Applications of confocal microscopy to the study of myelin development and neuron structure. / Staugaitis, S. M.; Rowan, T.; Sanes, Dan; Colman, D. R.; Smith, P. R.

In: Journal of Electron Microscopy Technique, Vol. 18, No. 1, 1991, p. 31-37.

Research output: Contribution to journalArticle

Staugaitis, S. M. ; Rowan, T. ; Sanes, Dan ; Colman, D. R. ; Smith, P. R. / Applications of confocal microscopy to the study of myelin development and neuron structure. In: Journal of Electron Microscopy Technique. 1991 ; Vol. 18, No. 1. pp. 31-37.
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