Analgesic efficacy and safety of an: Intraoral lidocaine patch

Elliot V. Hersh, Milton I. Houpt, Stephen A. Cooper, Roy S. Feldman, Mark Wolff, Lawrence M. Levin

Research output: Contribution to journalArticle

Abstract

The effectiveness of intraoral lidocaine patches was tested by asking participants to rate the pain experienced after insertions of a 25-gauge needle. Needlesticks were performed at baseline and at various time points after patch placement. Each needlestick included contact with the periosteum. Lidocaine patches achieved significantly better analgesia than the placebo within 2.5 to five minutes after placement. Drug-related side effects were minimal and venous blood levels of lidocaine were low, averaging 10 to 14 times less than those achieved with a typical injection of lidocaine plus epinephrine. The authors conclude that the lidocaine patches used in this study are effective and safe in reducing needle insertion pain in adults.

Original languageEnglish (US)
Pages (from-to)1626-1634
Number of pages9
JournalJournal of the American Dental Association
Volume127
Issue number11
StatePublished - Nov 1996

Fingerprint

Lidocaine
Analgesics
Safety
Needlestick Injuries
Needles
Pain
Periosteum
Drug-Related Side Effects and Adverse Reactions
Analgesia
Epinephrine
Placebos
Injections

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Hersh, E. V., Houpt, M. I., Cooper, S. A., Feldman, R. S., Wolff, M., & Levin, L. M. (1996). Analgesic efficacy and safety of an: Intraoral lidocaine patch. Journal of the American Dental Association, 127(11), 1626-1634.

Analgesic efficacy and safety of an : Intraoral lidocaine patch. / Hersh, Elliot V.; Houpt, Milton I.; Cooper, Stephen A.; Feldman, Roy S.; Wolff, Mark; Levin, Lawrence M.

In: Journal of the American Dental Association, Vol. 127, No. 11, 11.1996, p. 1626-1634.

Research output: Contribution to journalArticle

Hersh, EV, Houpt, MI, Cooper, SA, Feldman, RS, Wolff, M & Levin, LM 1996, 'Analgesic efficacy and safety of an: Intraoral lidocaine patch', Journal of the American Dental Association, vol. 127, no. 11, pp. 1626-1634.
Hersh EV, Houpt MI, Cooper SA, Feldman RS, Wolff M, Levin LM. Analgesic efficacy and safety of an: Intraoral lidocaine patch. Journal of the American Dental Association. 1996 Nov;127(11):1626-1634.
Hersh, Elliot V. ; Houpt, Milton I. ; Cooper, Stephen A. ; Feldman, Roy S. ; Wolff, Mark ; Levin, Lawrence M. / Analgesic efficacy and safety of an : Intraoral lidocaine patch. In: Journal of the American Dental Association. 1996 ; Vol. 127, No. 11. pp. 1626-1634.
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