Adaptation to contingencies in macaque primary visual cortex

Matteo Carandini, Horace B. Barlow, Lawrence P. O'Keefe, Allen B. Poirson, J. Anthony Movshon

Research output: Contribution to journalArticle

Abstract

We tested the hypothesis that neurons in the primary visual cortex (V1) adapt selectively to contingencies in the attributes of visual stimuli. We recorded from single neurons in macaque V1 and measured the effects of adaptation either to the sum of two gratings (compound stimulus) or to the individual gratings. According to our hypothesis, there would be a component of adaptation that is specific to the compound stimulus. In a first series of experiments, the two gratings differed in orientation. One grating had optimal orientation and the other was orthogonal to it, and therefore did not activate the neuron under study. These experiments provided evidence in favour of our hypothesis. In most cells adaptation to the compound stimulus reduced responses to the compound stimulus more than it reduced responses to the optimal grating, and the responses to the compound stimulus were reduced more by adaptation to the compound stimulus than by adaptation to the individual gratings. This suggests that a component of adaptation was specific to (and caused by) the simultaneous presence of the two orientations in the compound stimulus. To test whether V1 neurons could adapt to other contingencies in the stimulus attributes, we performed a second series of experiments, in which the component gratings were parallel but differed in spatial frequency, and were both effective in activating the neuron under study. These experiments failed to reveal convincing contingent effects of adaptation, suggesting that neurons cannot adapt equally well to all types of contingency.

Original languageEnglish (US)
Pages (from-to)1149-1154
Number of pages6
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume352
Issue number1358
DOIs
StatePublished - Aug 29 1997

Fingerprint

Macaca
Visual Cortex
Neurons
neurons
Experiments
visual cortex
testing
cells

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Adaptation to contingencies in macaque primary visual cortex. / Carandini, Matteo; Barlow, Horace B.; O'Keefe, Lawrence P.; Poirson, Allen B.; Movshon, J. Anthony.

In: Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 352, No. 1358, 29.08.1997, p. 1149-1154.

Research output: Contribution to journalArticle

Carandini, Matteo ; Barlow, Horace B. ; O'Keefe, Lawrence P. ; Poirson, Allen B. ; Movshon, J. Anthony. / Adaptation to contingencies in macaque primary visual cortex. In: Philosophical Transactions of the Royal Society B: Biological Sciences. 1997 ; Vol. 352, No. 1358. pp. 1149-1154.
@article{bc9395e2d5df4786b04e6161d4350292,
title = "Adaptation to contingencies in macaque primary visual cortex",
abstract = "We tested the hypothesis that neurons in the primary visual cortex (V1) adapt selectively to contingencies in the attributes of visual stimuli. We recorded from single neurons in macaque V1 and measured the effects of adaptation either to the sum of two gratings (compound stimulus) or to the individual gratings. According to our hypothesis, there would be a component of adaptation that is specific to the compound stimulus. In a first series of experiments, the two gratings differed in orientation. One grating had optimal orientation and the other was orthogonal to it, and therefore did not activate the neuron under study. These experiments provided evidence in favour of our hypothesis. In most cells adaptation to the compound stimulus reduced responses to the compound stimulus more than it reduced responses to the optimal grating, and the responses to the compound stimulus were reduced more by adaptation to the compound stimulus than by adaptation to the individual gratings. This suggests that a component of adaptation was specific to (and caused by) the simultaneous presence of the two orientations in the compound stimulus. To test whether V1 neurons could adapt to other contingencies in the stimulus attributes, we performed a second series of experiments, in which the component gratings were parallel but differed in spatial frequency, and were both effective in activating the neuron under study. These experiments failed to reveal convincing contingent effects of adaptation, suggesting that neurons cannot adapt equally well to all types of contingency.",
author = "Matteo Carandini and Barlow, {Horace B.} and O'Keefe, {Lawrence P.} and Poirson, {Allen B.} and Movshon, {J. Anthony}",
year = "1997",
month = "8",
day = "29",
doi = "10.1098/rstb.1997.0098",
language = "English (US)",
volume = "352",
pages = "1149--1154",
journal = "Philosophical Transactions of the Royal Society B: Biological Sciences",
issn = "0962-8436",
publisher = "Royal Society of London",
number = "1358",

}

TY - JOUR

T1 - Adaptation to contingencies in macaque primary visual cortex

AU - Carandini, Matteo

AU - Barlow, Horace B.

AU - O'Keefe, Lawrence P.

AU - Poirson, Allen B.

AU - Movshon, J. Anthony

PY - 1997/8/29

Y1 - 1997/8/29

N2 - We tested the hypothesis that neurons in the primary visual cortex (V1) adapt selectively to contingencies in the attributes of visual stimuli. We recorded from single neurons in macaque V1 and measured the effects of adaptation either to the sum of two gratings (compound stimulus) or to the individual gratings. According to our hypothesis, there would be a component of adaptation that is specific to the compound stimulus. In a first series of experiments, the two gratings differed in orientation. One grating had optimal orientation and the other was orthogonal to it, and therefore did not activate the neuron under study. These experiments provided evidence in favour of our hypothesis. In most cells adaptation to the compound stimulus reduced responses to the compound stimulus more than it reduced responses to the optimal grating, and the responses to the compound stimulus were reduced more by adaptation to the compound stimulus than by adaptation to the individual gratings. This suggests that a component of adaptation was specific to (and caused by) the simultaneous presence of the two orientations in the compound stimulus. To test whether V1 neurons could adapt to other contingencies in the stimulus attributes, we performed a second series of experiments, in which the component gratings were parallel but differed in spatial frequency, and were both effective in activating the neuron under study. These experiments failed to reveal convincing contingent effects of adaptation, suggesting that neurons cannot adapt equally well to all types of contingency.

AB - We tested the hypothesis that neurons in the primary visual cortex (V1) adapt selectively to contingencies in the attributes of visual stimuli. We recorded from single neurons in macaque V1 and measured the effects of adaptation either to the sum of two gratings (compound stimulus) or to the individual gratings. According to our hypothesis, there would be a component of adaptation that is specific to the compound stimulus. In a first series of experiments, the two gratings differed in orientation. One grating had optimal orientation and the other was orthogonal to it, and therefore did not activate the neuron under study. These experiments provided evidence in favour of our hypothesis. In most cells adaptation to the compound stimulus reduced responses to the compound stimulus more than it reduced responses to the optimal grating, and the responses to the compound stimulus were reduced more by adaptation to the compound stimulus than by adaptation to the individual gratings. This suggests that a component of adaptation was specific to (and caused by) the simultaneous presence of the two orientations in the compound stimulus. To test whether V1 neurons could adapt to other contingencies in the stimulus attributes, we performed a second series of experiments, in which the component gratings were parallel but differed in spatial frequency, and were both effective in activating the neuron under study. These experiments failed to reveal convincing contingent effects of adaptation, suggesting that neurons cannot adapt equally well to all types of contingency.

UR - http://www.scopus.com/inward/record.url?scp=0031590135&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031590135&partnerID=8YFLogxK

U2 - 10.1098/rstb.1997.0098

DO - 10.1098/rstb.1997.0098

M3 - Article

VL - 352

SP - 1149

EP - 1154

JO - Philosophical Transactions of the Royal Society B: Biological Sciences

JF - Philosophical Transactions of the Royal Society B: Biological Sciences

SN - 0962-8436

IS - 1358

ER -