Active CMOS biochip for time-resolved fluorescence detection

George Patounakis, K. L. Shepard, Rastislav Levicky

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes the design of an active CMOS biosensor array for fluorescence-based assays which enables time-gated, time-resolved fluorescence spectroscopy. The array is sensitive to photon densities as low as 1.15 × 108/cm2, has a dynamic range of over 74 dB, and has sub-nanosecond timing resolution. High sensitivity is achieved through subsampling and averaging.

Original languageEnglish (US)
Title of host publication2005 Symposium on VLSI Circuits - Digest of Technical Papers
Pages68-71
Number of pages4
Volume2005
DOIs
StatePublished - 2005
Event2005 Symposium on VLSI Circuits - Kyoto, Japan
Duration: Jun 16 2005Jun 18 2005

Other

Other2005 Symposium on VLSI Circuits
CountryJapan
CityKyoto
Period6/16/056/18/05

Fingerprint

Biochips
Fluorescence spectroscopy
Biosensors
Assays
Photons
Fluorescence

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Patounakis, G., Shepard, K. L., & Levicky, R. (2005). Active CMOS biochip for time-resolved fluorescence detection. In 2005 Symposium on VLSI Circuits - Digest of Technical Papers (Vol. 2005, pp. 68-71). [1469336] https://doi.org/10.1109/VLSIC.2005.1469336

Active CMOS biochip for time-resolved fluorescence detection. / Patounakis, George; Shepard, K. L.; Levicky, Rastislav.

2005 Symposium on VLSI Circuits - Digest of Technical Papers. Vol. 2005 2005. p. 68-71 1469336.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Patounakis, G, Shepard, KL & Levicky, R 2005, Active CMOS biochip for time-resolved fluorescence detection. in 2005 Symposium on VLSI Circuits - Digest of Technical Papers. vol. 2005, 1469336, pp. 68-71, 2005 Symposium on VLSI Circuits, Kyoto, Japan, 6/16/05. https://doi.org/10.1109/VLSIC.2005.1469336
Patounakis G, Shepard KL, Levicky R. Active CMOS biochip for time-resolved fluorescence detection. In 2005 Symposium on VLSI Circuits - Digest of Technical Papers. Vol. 2005. 2005. p. 68-71. 1469336 https://doi.org/10.1109/VLSIC.2005.1469336
Patounakis, George ; Shepard, K. L. ; Levicky, Rastislav. / Active CMOS biochip for time-resolved fluorescence detection. 2005 Symposium on VLSI Circuits - Digest of Technical Papers. Vol. 2005 2005. pp. 68-71
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