Acid-mediated topological control in a functionalized foldamer

Peter C. Knipe, Sam Thompson, Andrew Hamilton

Research output: Contribution to journalArticle


Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

Original languageEnglish (US)
Pages (from-to)6521-6524
Number of pages4
JournalChemical Communications
Issue number39
StatePublished - 2016


ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

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