A tweaking principle for executive control: Neuronal circuit mechanism for rule-based task switching and conflict resolution

Salva Ardid, Xiao-Jing Wang

Research output: Contribution to journalArticle

Abstract

A hallmark of executive control is the brain's agility to shift between different tasks depending on the behavioral rule currently in play. In this work, we propose a "tweaking hypothesis" for task switching: a weak rule signal provides a small bias that is dramatically amplified by reverberating attractor dynamics in neural circuits for stimulus categorization and action selection, leading to an all-or-none reconfiguration of sensory-motor mapping. Based on this principle, we developed a biologically realistic model with multiple modules for task switching. We found that the model quantitatively accounts for complex task switching behavior: switch cost, congruency effect, and task-response interaction; as well as monkey's single-neuron activity associated with task switching. The model yields several testable predictions, in particular, that category-selective neurons play a key role in resolving sensory-motor conflict. This work represents a neural circuit model for task switching and sheds insights in the brain mechanism of a fundamental cognitive capability.

Original languageEnglish (US)
Pages (from-to)19504-19517
Number of pages14
JournalJournal of Neuroscience
Volume33
Issue number50
DOIs
StatePublished - 2013

Fingerprint

Executive Function
Negotiating
Switch Genes
Neurons
Brain
Haplorhini
Costs and Cost Analysis
Conflict (Psychology)

Keywords

  • Attractor dynamics
  • Congruency effect
  • Flexible behavior
  • Sensory-motor conflict
  • Switch cost
  • Top-down control

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

A tweaking principle for executive control : Neuronal circuit mechanism for rule-based task switching and conflict resolution. / Ardid, Salva; Wang, Xiao-Jing.

In: Journal of Neuroscience, Vol. 33, No. 50, 2013, p. 19504-19517.

Research output: Contribution to journalArticle

@article{9154559504804d70b028b1ae1fc95ce8,
title = "A tweaking principle for executive control: Neuronal circuit mechanism for rule-based task switching and conflict resolution",
abstract = "A hallmark of executive control is the brain's agility to shift between different tasks depending on the behavioral rule currently in play. In this work, we propose a {"}tweaking hypothesis{"} for task switching: a weak rule signal provides a small bias that is dramatically amplified by reverberating attractor dynamics in neural circuits for stimulus categorization and action selection, leading to an all-or-none reconfiguration of sensory-motor mapping. Based on this principle, we developed a biologically realistic model with multiple modules for task switching. We found that the model quantitatively accounts for complex task switching behavior: switch cost, congruency effect, and task-response interaction; as well as monkey's single-neuron activity associated with task switching. The model yields several testable predictions, in particular, that category-selective neurons play a key role in resolving sensory-motor conflict. This work represents a neural circuit model for task switching and sheds insights in the brain mechanism of a fundamental cognitive capability.",
keywords = "Attractor dynamics, Congruency effect, Flexible behavior, Sensory-motor conflict, Switch cost, Top-down control",
author = "Salva Ardid and Xiao-Jing Wang",
year = "2013",
doi = "10.1523/JNEUROSCI.1356-13.2013",
language = "English (US)",
volume = "33",
pages = "19504--19517",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "50",

}

TY - JOUR

T1 - A tweaking principle for executive control

T2 - Neuronal circuit mechanism for rule-based task switching and conflict resolution

AU - Ardid, Salva

AU - Wang, Xiao-Jing

PY - 2013

Y1 - 2013

N2 - A hallmark of executive control is the brain's agility to shift between different tasks depending on the behavioral rule currently in play. In this work, we propose a "tweaking hypothesis" for task switching: a weak rule signal provides a small bias that is dramatically amplified by reverberating attractor dynamics in neural circuits for stimulus categorization and action selection, leading to an all-or-none reconfiguration of sensory-motor mapping. Based on this principle, we developed a biologically realistic model with multiple modules for task switching. We found that the model quantitatively accounts for complex task switching behavior: switch cost, congruency effect, and task-response interaction; as well as monkey's single-neuron activity associated with task switching. The model yields several testable predictions, in particular, that category-selective neurons play a key role in resolving sensory-motor conflict. This work represents a neural circuit model for task switching and sheds insights in the brain mechanism of a fundamental cognitive capability.

AB - A hallmark of executive control is the brain's agility to shift between different tasks depending on the behavioral rule currently in play. In this work, we propose a "tweaking hypothesis" for task switching: a weak rule signal provides a small bias that is dramatically amplified by reverberating attractor dynamics in neural circuits for stimulus categorization and action selection, leading to an all-or-none reconfiguration of sensory-motor mapping. Based on this principle, we developed a biologically realistic model with multiple modules for task switching. We found that the model quantitatively accounts for complex task switching behavior: switch cost, congruency effect, and task-response interaction; as well as monkey's single-neuron activity associated with task switching. The model yields several testable predictions, in particular, that category-selective neurons play a key role in resolving sensory-motor conflict. This work represents a neural circuit model for task switching and sheds insights in the brain mechanism of a fundamental cognitive capability.

KW - Attractor dynamics

KW - Congruency effect

KW - Flexible behavior

KW - Sensory-motor conflict

KW - Switch cost

KW - Top-down control

UR - http://www.scopus.com/inward/record.url?scp=84889796831&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889796831&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.1356-13.2013

DO - 10.1523/JNEUROSCI.1356-13.2013

M3 - Article

C2 - 24336717

AN - SCOPUS:84889796831

VL - 33

SP - 19504

EP - 19517

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 50

ER -