Teoreticheskaia model' upakovki DNK v golovke faga.

Translated title of the contribution: A theoretical model of DNA packaging in the phage head

I. S. Gabashvili, A. I. Grosberg, D. V. Kuznetsov, G. M. Mrevlishvili

    Research output: Contribution to journalArticle

    Abstract

    Statistical model of dsDNA packaging to icosahedral bacteriophage capsid is presented. The model describes intraphage DNA as a globule, i.e. intramolecular liquid crystal. We analyse the free energy of DNA, which has a globulized part inside the phage capsid and coil-like tail outside it. Conditions when processes of DNA movement into capsid or back are thermodynamically favorable are investigated. These processes are not accompanied with any thermal effects. It is not "all or none" type process, i.e. intermediate stable states are possible. The role of DNA interaction with the capsid inner wall is considered. The essential model abilities for qualitative explanation of experimental data are exhibited.

    Original languageUndefined
    Pages (from-to)780-787
    Number of pages8
    JournalBiofizika
    Volume36
    Issue number5
    StatePublished - Sep 1991

    Fingerprint

    DNA Packaging
    Capsid
    Bacteriophages
    Theoretical Models
    DNA
    Liquid Crystals
    Statistical Models
    Product Packaging
    Hot Temperature

    ASJC Scopus subject areas

    • Biophysics

    Cite this

    Gabashvili, I. S., Grosberg, A. I., Kuznetsov, D. V., & Mrevlishvili, G. M. (1991). Teoreticheskaia model' upakovki DNK v golovke faga. Biofizika, 36(5), 780-787.

    Teoreticheskaia model' upakovki DNK v golovke faga. / Gabashvili, I. S.; Grosberg, A. I.; Kuznetsov, D. V.; Mrevlishvili, G. M.

    In: Biofizika, Vol. 36, No. 5, 09.1991, p. 780-787.

    Research output: Contribution to journalArticle

    Gabashvili, IS, Grosberg, AI, Kuznetsov, DV & Mrevlishvili, GM 1991, 'Teoreticheskaia model' upakovki DNK v golovke faga.', Biofizika, vol. 36, no. 5, pp. 780-787.
    Gabashvili IS, Grosberg AI, Kuznetsov DV, Mrevlishvili GM. Teoreticheskaia model' upakovki DNK v golovke faga. Biofizika. 1991 Sep;36(5):780-787.
    Gabashvili, I. S. ; Grosberg, A. I. ; Kuznetsov, D. V. ; Mrevlishvili, G. M. / Teoreticheskaia model' upakovki DNK v golovke faga. In: Biofizika. 1991 ; Vol. 36, No. 5. pp. 780-787.
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