A synthetic analogue of the carboxylate-binding pocket of vancomycin

Michael J. Mann, Nalin Pant, Andrew Hamilton

Research output: Contribution to journalArticle

Abstract

A synthetic analogue of the right-hand ring of vancomycin, the region in the antibiotic which contains the pocket for binding to the terminal carboxylate of D-Ala-D-Ala containing peptides, has been prepared and shows structural and spectroscopic similarity to the natural molecule.

Original languageEnglish (US)
Pages (from-to)158-160
Number of pages3
JournalJournal of the Chemical Society D: Chemical Communications
Issue number2
DOIs
StatePublished - 1986

Fingerprint

Antibiotics
Vancomycin
Peptides
Hand
Anti-Bacterial Agents
Molecules
alanylalanine

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

A synthetic analogue of the carboxylate-binding pocket of vancomycin. / Mann, Michael J.; Pant, Nalin; Hamilton, Andrew.

In: Journal of the Chemical Society D: Chemical Communications, No. 2, 1986, p. 158-160.

Research output: Contribution to journalArticle

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