A robust route towards functionalized pyrrolizidines as precursors for daphniphyllum alkaloids

Michael Pangerl, Ignaz Höhlein, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

A diastereoselective Fráter-Seebach-type alkylation provides access to a highly functionalized pyrrolizidine, which could serve as a key building block for the total synthesis of ÂDaphniphyllum alkaloids, such as oldhamine A.

Original languageEnglish (US)
Article numberST-2013-B1030-L
Pages (from-to)741-745
Number of pages5
JournalSynlett
Volume25
Issue number5
DOIs
StatePublished - 2014

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Alkylation
Alkaloids

Keywords

  • asymmetric synthesis
  • Daphniphyllum alkaloids
  • heteroÂcycles
  • oldhamine A
  • pyrrolizidines

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

A robust route towards functionalized pyrrolizidines as precursors for daphniphyllum alkaloids. / Pangerl, Michael; Höhlein, Ignaz; Trauner, Dirk.

In: Synlett, Vol. 25, No. 5, ST-2013-B1030-L, 2014, p. 741-745.

Research output: Contribution to journalArticle

Pangerl, M, Höhlein, I & Trauner, D 2014, 'A robust route towards functionalized pyrrolizidines as precursors for daphniphyllum alkaloids', Synlett, vol. 25, no. 5, ST-2013-B1030-L, pp. 741-745. https://doi.org/10.1055/s-0033-1340677
Pangerl, Michael ; Höhlein, Ignaz ; Trauner, Dirk. / A robust route towards functionalized pyrrolizidines as precursors for daphniphyllum alkaloids. In: Synlett. 2014 ; Vol. 25, No. 5. pp. 741-745.
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