A model of cell sorting

D. Sulsky, S. Childress, Jerome Percus

Research output: Contribution to journalArticle

Abstract

Voronoi polygons are introduced as a suitable representation for a two-dimensional cell sheet. These polygons are defined in terms of a finite number of points, making numerical simulations tractable and yet allowing cells to change neighbors and their shape in response to deforming forces without leaving gaps in the tissue. Using this geometry and an extension of the equilibrium theory proposed by Steinberg to drive the motion, simulations of rounding of uneven tissue and engulfment of two intact tissues are carried out.

Original languageEnglish (US)
Pages (from-to)275-301
Number of pages27
JournalJournal of Theoretical Biology
Volume106
Issue number3
DOIs
StatePublished - Feb 7 1984

Fingerprint

Sorting
sorting
Polygon
Cells
Tissue
Motion Simulation
Voronoi
Rounding
Cell
equilibrium theory
cells
Numerical Simulation
Model
Geometry
Computer simulation
tissues

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Sulsky, D., Childress, S., & Percus, J. (1984). A model of cell sorting. Journal of Theoretical Biology, 106(3), 275-301. https://doi.org/10.1016/0022-5193(84)90031-6

A model of cell sorting. / Sulsky, D.; Childress, S.; Percus, Jerome.

In: Journal of Theoretical Biology, Vol. 106, No. 3, 07.02.1984, p. 275-301.

Research output: Contribution to journalArticle

Sulsky, D, Childress, S & Percus, J 1984, 'A model of cell sorting', Journal of Theoretical Biology, vol. 106, no. 3, pp. 275-301. https://doi.org/10.1016/0022-5193(84)90031-6
Sulsky, D. ; Childress, S. ; Percus, Jerome. / A model of cell sorting. In: Journal of Theoretical Biology. 1984 ; Vol. 106, No. 3. pp. 275-301.
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