A larger spectrum of severe HIV-1-related disease in intravenous drug users in New York City

Rand L. Stoneburner, Don Des Jarlais, Diane Benezra, Leo Gorelkin, Jo L. Sotheran, Samuel R. Friedman, Stephen Schultz, Michael Marmor, Donna Mildvan, Robert Maslansky

Research output: Contribution to journalArticle

Abstract

Increasing mortality in intravenous (IV) drug users not reported to surveillance as acquired immunodeficiency syndrome (AIDS) has occurred in New York City coincident with the AIDS epidemic. From 1981 to 1986, narcotics-related deaths increased on average 32% per year from 492 in 1981 to 1996 in 1986. This increase included deaths from AIDS increasing from 0 to 905 and deaths from other causes, many of which were infectious diseases, increasing from 492 to 1091. Investigations of these deaths suggest a causal association with human immunodeficiency virus (HIV) infection. These deaths may represent a spectrum of HIV-related disease that has not been identified through AIDS surveillance and has resulted in a large underestimation of the impact of AIDS on IV drug users and blacks and Hispanics.

Original languageEnglish (US)
Pages (from-to)916-919
Number of pages4
JournalScience
Volume242
Issue number4880
DOIs
StatePublished - Jan 1 1988

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Drug Users
HIV-1
Acquired Immunodeficiency Syndrome
Virus Diseases
HIV
Narcotics
Hispanic Americans
Communicable Diseases
Cause of Death
Mortality

ASJC Scopus subject areas

  • General

Cite this

Stoneburner, R. L., Des Jarlais, D., Benezra, D., Gorelkin, L., Sotheran, J. L., Friedman, S. R., ... Maslansky, R. (1988). A larger spectrum of severe HIV-1-related disease in intravenous drug users in New York City. Science, 242(4880), 916-919. https://doi.org/10.1126/science.3187532

A larger spectrum of severe HIV-1-related disease in intravenous drug users in New York City. / Stoneburner, Rand L.; Des Jarlais, Don; Benezra, Diane; Gorelkin, Leo; Sotheran, Jo L.; Friedman, Samuel R.; Schultz, Stephen; Marmor, Michael; Mildvan, Donna; Maslansky, Robert.

In: Science, Vol. 242, No. 4880, 01.01.1988, p. 916-919.

Research output: Contribution to journalArticle

Stoneburner, RL, Des Jarlais, D, Benezra, D, Gorelkin, L, Sotheran, JL, Friedman, SR, Schultz, S, Marmor, M, Mildvan, D & Maslansky, R 1988, 'A larger spectrum of severe HIV-1-related disease in intravenous drug users in New York City', Science, vol. 242, no. 4880, pp. 916-919. https://doi.org/10.1126/science.3187532
Stoneburner RL, Des Jarlais D, Benezra D, Gorelkin L, Sotheran JL, Friedman SR et al. A larger spectrum of severe HIV-1-related disease in intravenous drug users in New York City. Science. 1988 Jan 1;242(4880):916-919. https://doi.org/10.1126/science.3187532
Stoneburner, Rand L. ; Des Jarlais, Don ; Benezra, Diane ; Gorelkin, Leo ; Sotheran, Jo L. ; Friedman, Samuel R. ; Schultz, Stephen ; Marmor, Michael ; Mildvan, Donna ; Maslansky, Robert. / A larger spectrum of severe HIV-1-related disease in intravenous drug users in New York City. In: Science. 1988 ; Vol. 242, No. 4880. pp. 916-919.
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