A functional link between area MSTd and heading perception based on vestibular signals

Yong Gu, Gregory C. DeAngelis, Dora Angelaki

Research output: Contribution to journalArticle

Abstract

Recent findings of vestibular responses in part of the visual cortex - the dorsal medial superior temporal area (MSTd) - indicate that vestibular signals might contribute to cortical processes that mediate the perception of self-motion. We tested this hypothesis in monkeys trained to perform a fine heading discrimination task solely on the basis of inertial motion cues. The sensitivity of the neuronal responses was typically lower than that of psychophysical performance, and only the most sensitive neurons rivaled behavioral performance. Responses recorded in MSTd were significantly correlated with perceptual decisions, and the correlations were strongest for the most sensitive neurons. These results support a functional link between MSTd and heading perception based on inertial motion cues. These cues seem mainly to be of vestibular origin, as labyrinthectomy produced a marked elevation of psychophysical thresholds and abolished MSTd responses. This study provides evidence that links single-unit activity to spatial perception mediated by vestibular signals, and supports the idea that the role of MSTd in self-motion perception extends beyond optic flow processing.

Original languageEnglish (US)
Pages (from-to)1038-1047
Number of pages10
JournalNature Neuroscience
Volume10
Issue number8
DOIs
StatePublished - Aug 1 2007

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Motion Perception
Cues
Optic Flow
Neurons
Visual Cortex
Haplorhini
Discrimination (Psychology)

ASJC Scopus subject areas

  • Neuroscience(all)

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A functional link between area MSTd and heading perception based on vestibular signals. / Gu, Yong; DeAngelis, Gregory C.; Angelaki, Dora.

In: Nature Neuroscience, Vol. 10, No. 8, 01.08.2007, p. 1038-1047.

Research output: Contribution to journalArticle

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