A formal synthesis of crinipellin B based on the arene-alkene meta- photocycloaddition reaction

Paul A. Wender, Timothy M. Dore

Research output: Contribution to journalArticle

Abstract

Starting from triethyl phosphonopropionate and 3-nitro-2-methylbenzoic acid, a formal synthesis of crinipellin B was achieved. The strategy draws on the use of a novel version of the arene-alkene meta-photocycloaddition reaction that proceeds with the generation of 4 rings and 4 quaternary stereocenters in one synthetic operation.

Original languageEnglish (US)
Pages (from-to)8589-8592
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number47
DOIs
StatePublished - Nov 19 1998

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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