A foot in the door: How the chromatin modifier Brg1 and Pax6 jointly potentiate adult neurogenesis

Xavier H. Jaglin, Gord Fishell

Research output: Contribution to journalShort survey

Abstract

Transcription factors and chromatin modifiers are known to contribute to cell specification. However, whether and how they jointly act is poorly understood. In this issue of Cell Stem Cell, Ninkovic et al. show that Pax6 and Brg1 cooperate to modulate gene expression in order to direct neurogenic fate in the olfactory bulb.

Original languageEnglish (US)
Pages (from-to)373-374
Number of pages2
JournalCell Stem Cell
Volume13
Issue number4
DOIs
StatePublished - Oct 3 2013

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ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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